[HTML][HTML] Type 2 innate lymphoid cells are protective against hepatic ischaemia/reperfusion injury

Q Cao, R Wang, Z Niu, T Chen, F Azmi, SA Read… - JHEP Reports, 2023 - Elsevier
Background and Aims Although type 2 innate lymphoid cells (ILC2s) were originally found to
be liver-resident lymphocytes, the role and importance of ILC2 in liver injury remains poorly …

Extracellular vesicles as potential biomarkers and treatment options for liver failure: A systematic review up to March 2022

W Lu, H Tang, S Li, L Bai, Y Chen - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Extracellular vesicles (EVs) carrying functional cargoes are emerging as
biomarkers and treatment strategies in multiple liver diseases. Nevertheless, the potential of …

Sex differences in hepatic ischemia‒reperfusion injury: a cross-sectional study

Z Li, S Lu, B Qian, Z Meng, Y Zhou, D Chen, B Chen… - Scientific Reports, 2023 - nature.com
Several studies have shown that males suffer more severe damage than females in the
process of ischemia and reperfusion of the brain, heart and kidney. Accordingly, our study …

The distinct innate immune response of warm ischemic injured livers during continuous normothermic machine perfusion

J Blondeel, N Gilbo, V Heedfeld, T Wylin… - International Journal of …, 2023 - mdpi.com
Although normothermic machine perfusion (NMP) provides superior preservation of liver
grafts compared to static cold storage and allows for viability testing of high-risk grafts, its …

Activation of the PPARγ/NF-κB pathway by A-MPDA@ Fe 3 O 4@ PVP via scavenging reactive oxygen species to alleviate hepatic ischemia-reperfusion injury

D Mo, W Cui, L Chen, J Meng, Y Sun, K Cai… - Journal of Materials …, 2024 - pubs.rsc.org
Hepatic ischemia-reperfusion injury (IRI) is a common pathological process during
hepatectomy and liver transplantation and the two primary reasons for hepatic IRI are …

A bibliometric and visualized analysis of hepatic ischemia-reperfusion injury (HIRI) from 2002 to 2021

X Lin, Y Zhou, L Ye, B Wang, Y Jiao, W Yu, P Gao… - Heliyon, 2023 - cell.com
Hepatic ischemia-reperfusion injury (HIRI) is a complex pathological phenomenon
dominated by the innate immune system and involves a variety of immune cells. This …

Hepatocellular SETDB1 regulates hepatic ischemia-reperfusion injury through targeting lysine methylation of ASK1 signal

K Xia, T Wang, Z Chen, J Guo, B Yu, Q Chen, T Qiu… - Research, 2023 - spj.science.org
Background: Hepatic ischemia-reperfusion injury (HIRI) stands as an unavoidable
complication arising from liver surgery, profoundly intertwined with its prognosis. The role of …

Extracellular vesicles containing GAS6 protect the liver from ischemia-reperfusion injury by enhancing macrophage efferocytosis via MerTK-ERK-COX2 signaling

L Miao, C Yu, G Guan, X Luan, X Jin, M Pan… - Cell Death …, 2024 - nature.com
Hepatic ischemia-reperfusion injury (HIRI) is a significant issue during liver transplantation
and surgery, contributing to the liver failure or even mortality. Although extracellular vesicles …

Hepatocyte-specific Sox9 knockout ameliorates acute liver injury by suppressing SHP signaling and improving mitochondrial function

D Qin, R Wang, J Ji, D Wang, Y Lu, S Cao, Y Chen… - Cell & Bioscience, 2023 - Springer
Abstract Background and Aims Sex determining region Y related high-mobility group box
protein 9 (Sox9) is expressed in a subset of hepatocytes, and it is important for chronic liver …

Liver ischemia-reperfusion injury: From trigger loading to shot firing

E Felli, E Felli, EM Muttillo, T Urade… - Liver …, 2023 - journals.lww.com
An ischemia-reperfusion injury (IRI) results from a prolonged ischemic insult followed by the
restoration of blood perfusion, being a common cause of morbidity and mortality, especially …