Astrocytes are key active elements of the brain that contribute to information processing.
They not only provide neurons with metabolic and structural support, but also regulate …

Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

An inverse association has been observed between dietary intake of lycopene and the risk
of prostate cancer. We investigated the effects of lycopene supplementation in patients with …

The idea that the gap junction family of proteins, connexins, are tumour suppressors has
been widely supported through numerous cancer models. However, the paradigm that …

The predominantly autosomal dominant disorder, oculodentodigital dysplasia (ODDD) has
high penetrance with intra‐and interfamilial phenotypic variability. Abnormalities observed in …

Direct communication between cells, mediated by gap junctions, is nowadays considered as
an indispensable mechanism in the maintenance of cellular homeostasis. In fact, gap …

A hallmark of astrocytic tumors is their infiltrative nature. Although their aggressive and
typically widespread dispersal in the adult brain differs fundamentally from that of other brain …

Connexins are tumor suppressors, and human breast connexin 26 (Cx26) and connexin 43
(Cx43) gap junctions are often down-regulated in breast cancer. We previously showed that …

Connexins, the family of proteins that form vertebrate gap junctions, have key roles during
development and in the adult. Previously, the physiological actions of connexins have been …

Reduced gap junction activity has long been implicated in tumorigenesis. To elucidate the
potential role of intercellular communication in melanoma development, we examined gap …