Role of microRNAs in regulating cell proliferation, metastasis and chemoresistance and their applications as cancer biomarkers in small cell lung cancer

M Pandey, A Mukhopadhyay, SK Sharawat… - Biochimica et Biophysica …, 2021 - Elsevier
Small cell lung cancer (SCLC), a smoking-related highly aggressive neuroendocrine cancer,
is characterized by rapid cell proliferation, early metastatic dissemination, and early relapse …

[HTML][HTML] Non-Coding RNAs as key regulators in lung cancer

I Gilyazova, G Gimalova, A Nizamova… - International journal of …, 2023 - mdpi.com
For several decades, most lung cancer investigations have focused on the search for
mutations in candidate genes; however, in the last decade, due to the fact that most of the …

[HTML][HTML] Exosomal miRNA-205 promotes breast cancer chemoresistance and tumorigenesis through E2F1

Y Zhao, LJ Jin, XY Zhang - Aging (albany NY), 2021 - ncbi.nlm.nih.gov
Breast cancer (BC) is a common malignant tumor in females. The challenge in treating BC is
overcoming chemoresistance. Exosome-mediated transfer of miRNAs is a molecule-shuttle …

[HTML][HTML] The uprise of RNA biology in neuroendocrine neoplasms: altered splicing and RNA species unveil translational opportunities

R Blázquez-Encinas, MT Moreno-Montilla… - Reviews in Endocrine …, 2023 - Springer
Neuroendocrine neoplasms (NENs) comprise a highly heterogeneous group of tumors
arising from the diffuse neuroendocrine system. NENs mainly originate in gastrointestinal …

[HTML][HTML] The advances in epigenetics for cancer radiotherapy

Y Wang, Y Han, Y Jin, Q He, Z Wang - International Journal of Molecular …, 2022 - mdpi.com
Cancer is an important factor threatening human life and health; in recent years, its morbidity
and mortality remain high and demosntrate an upward trend. It is of great significance to …

Repression of linc01555 up-regulates angiomotin-p130 via the microRNA-122-5p/clic1 axis to impact vasculogenic mimicry-mediated chemotherapy resistance in …

D Li, YW Shen, H Ren, L Wang, J Yang, Y Wang - Cell Cycle, 2023 - Taylor & Francis
Long non-coding ribonucleic acid 01555 (linc01555) is a brand-new long non-coding RNA
(lncRNA) that acts a carcinogenic function in various cancers. However, its role in small cell …

[HTML][HTML] Molecular Signature of Small Cell Lung Cancer after Treatment Failure: The MCM Complex as Therapeutic Target

S Misono, K Mizuno, T Suetsugu, K Tanigawa… - Cancers, 2021 - mdpi.com
Simple Summary Small cell lung cancer (SCLC) is a fatal malignant tumor with a poor
prognosis for patients who relapse after first-line treatment. There are few effective …

[HTML][HTML] Exploring effective biomarkers and potential immune related gene in small cell lung cancer

Y Yunchu, A Miyanaga, K Matsuda, K Kamio… - Scientific Reports, 2024 - nature.com
Small cell lung cancer (SCLC) is well known as a highly malignant neuroendocrine tumor.
Immunotherapy combined with chemotherapy has become a standard treatment for …

[HTML][HTML] MiR-1246 regulates the PI3K/AKT signaling pathway by targeting PIK3AP1 and inhibits thyroid cancer cell proliferation and tumor growth

J Li, Z Zhang, J Hu, X Wan, W Huang, H Zhang… - Molecular and cellular …, 2022 - Springer
One of the most prevalent forms of endocrine malignancies is thyroid cancer. Herein, we
explored the mechanisms whereby miR-1246 is involved in thyroid cancer …

[HTML][HTML] Identification of potential target genes and crucial pathways in small cell lung cancer based on bioinformatic strategy and human samples

X Chen, L Wang, X Su, S Luo, X Tang, Y Huang - PLoS One, 2020 - journals.plos.org
Small cell lung cancer (SCLC) is a carcinoma of the lungs with strong invasion, poor
prognosis and resistant to multiple chemotherapeutic drugs. It has posed severe challenges …