Multifunctional Nanotheranostics for Overcoming the Blood–Brain Barrier

M Beygi, F Oroojalian, S Azizi‐Arani… - Advanced Functional …, 2024 - Wiley Online Library
The blood–brain barrier (BBB) is a tailored system of capillary endothelial cells intermixed
with tight junctions and adherent junctions that regulates the transport of various materials …

Parkinson's disease: a nanotheranostic approach targeting alpha-synuclein aggregation

FLG Zoey, M Palanivel, P Padmanabhan… - Frontiers in Cell and …, 2021 - frontiersin.org
Parkinson's disease (PD) is one of the most common neurodegenerative disorders that is
implicated in aging populations. As numerous developed nations are experiencing …

Enhancement of blood–brain barrier penetration and the neuroprotective effect of resveratrol

N Katila, R Duwa, S Bhurtel, S Khanal… - Journal of Controlled …, 2022 - Elsevier
Parkinson's disease (PD) is a debilitating neurodegenerative condition characterized by the
loss of dopaminergic neurons within the substantia nigra. The specific molecular …

The effects of polyvinyl alcohol-coated selenium nanoparticles on memory impairment in rats

N Hashemi-Firouzi, S Afshar, SS Asl… - Metabolic Brain …, 2022 - Springer
Some mineral elements exert beneficial neuroprotection, especially in the form of
nanoparticles. The aim of the present study was to evaluate the effects of selenium …

Naringenin-functionalized gold nanoparticles and their role in α-synuclein stabilization

A Maity, A Mondal, S Kundu, G Shome, R Misra… - Langmuir, 2023 - ACS Publications
Misfolding and self-assembly of several intrinsically disordered proteins into ordered β-sheet-
rich amyloid aggregates emerged as hallmarks of several neurodegenerative disorders …

Role of nanoparticle-conjugates and nanotheranostics in abrogating oxidative stress and ameliorating neuroinflammation

TA Patel, BD Kevadiya, N Bajwa, PA Singh, H Zheng… - Antioxidants, 2023 - mdpi.com
Oxidative stress is a deteriorating condition that arises due to an imbalance between the
reactive oxygen species and the antioxidant system or defense of the body. The key reasons …

[HTML][HTML] Pantothenate-encapsulated liposomes combined with exercise for effective inhibition of CRM1-mediated PKM2 translocation in Alzheimer's therapy

Y Chen, L Huang, Z Luo, D Han, W Luo, R Wan… - Journal of Controlled …, 2024 - Elsevier
Alzheimer's disease (AD) is a complex neurodegenerative condition characterized by
metabolic imbalances and neuroinflammation, posing a formidable challenge in medicine …

[HTML][HTML] Nanomedicines targeting the inflammasome as a promising therapeutic approach for cell senescence

S Chaturvedi, Z Naseem, SF El-Khamisy… - Seminars in Cancer …, 2022 - Elsevier
Technological advancements in the present era have enhanced drug discovery and
development. Nanomedicines are valuable pharmacotherapeutic tools against several …

A critical review on the role of nanotheranostics mediated approaches for targeting β amyloid in Alzheimer's

V Rastogi, A Jain, P Kumar, P Yadav… - Journal of Drug …, 2023 - Taylor & Francis
Alzheimer's is one of the most common neurodegenerative illnesses that affect brain cellular
function. In this disease, the neurons in the brain are considered to be decaying steadily but …

An In Vivo Study of a Rat Fluid-Percussion-Induced Traumatic Brain Injury Model with [11C]PBR28 and [18F]flumazenil PET Imaging

KK Ghosh, P Padmanabhan, CT Yang, Z Wang… - International Journal of …, 2021 - mdpi.com
Traumatic brain injury (TBI) modelled by lateral fluid percussion-induction (LFPI) in rats is a
widely used experimental rodent model to explore and understand the underlying cellular …