Rho proteins operate as key regulators of the cytoskeleton, cell morphology and trafficking.
Acting as molecular switches, the function of Rho GTPases is determined by guanosine …

Histone phosphorylation is a ubiquitous post-translational modification that allows
eukaryotic cells to rapidly respond to environmental stimuli. Despite correlative evidence …

Background: Tumor-associated macrophages (TAMs) are one of the most prominent tumor-
infiltrating immune cells in the tumor microenvironment (TME) of CRC and play a vital role in …

Abstract Objective Ependymin-Related Protein 1 (EPDR1) was recently identified as a
secreted human batokine regulating mitochondrial respiration linked to thermogenesis in …

Background As one of the most common malignant tumors in humans, lung cancer has
experienced a gradual increase in morbidity and mortality. This study examined prognosis …

Bone marrow stromal cell antigen 2 (BST2) is a type II transmembrane protein that serves
critical roles in antiretroviral defense in the innate immune response. In addition, it has been …

The finding of novel molecular markers for prediction or prognosis of invasiveness in
colorectal cancer (CRC) constitutes an appealing challenge. Here we show the up …

Background Bladder carcinoma is a common malignancy of the urinary system. The
previous study showed that EPDR1 expression was significantly related to the …

Background DNA methylation biomarkers in colorectal cancer (CRC) tissue hold potential as
prognostic indicators. However, individual studies have yielded heterogeneous results, and …

Epithelial ovarian cancer (EOC) is the main pathological type of ovarian cancer. In this study,
we found that ependymin-related 1 (EPDR1) was remarkably downregulated in EOC …