High-mobility group box 1 (HMGB1), a multifunctional nuclear protein, exists mainly within
the nucleus of all mammal eukaryotic cells. It is actively secreted by the necrotic cells as a …

Pulmonary fibrosis (PF) is characterised by several grades of chronic inflammation and
collagen deposition in the interalveolar space and is a hallmark of interstitial lung diseases …

The newly identified 13-series (T-series) resolvins (RvTs) regulate phagocyte functions and
accelerate resolution of infectious inflammation. Because severe acute respiratory syndrome …

Background This study aimed to investigate whether the active prescription of low-dose
aspirin during or prior to hospitalization affects mortality in patients with coronavirus disease …

Objectives There is conflicting evidence about the efficacy of statin use in regard to clinical
outcomes in patients with coronavirus disease 2019 (COVID-19). A systematic review and …

Background Repurposing the use of aspirin to treat hospitalized patients with COVID-19 is a
sensible approach. However, several previous studies showed conflicting results. This meta …

The impact of statins on COVID-19 remains unclear. This study aims to investigate whether
statin exposure assessed both in the population and in well-defined cohorts of COVID-19 …

The COVID-19 pandemic has led to over 100 million infections and over 3 million deaths
worldwide. Understanding its pathogenesis is crucial to guide prognostic and therapeutic …

Background The use of rosuvastatin plus colchicine and emtricitabine/tenofovir in
hospitalized patients with SARS-CoV-2 disease (COVID-19) has not been assessed. The …

Acute respiratory distress syndrome (ARDS) is an overwhelming inflammatory disorder of
the lung due to direct and indirect insults to the lungs. ARDS is characterized by increased …