Neurobiological alterations associated with PTSD

SM Southwick, LL Davis, DE Aikins… - Handbook of PTSD …, 2007 - books.google.com
Fear and life-threatening situations mobilize numerous brain regions, hormones, and
neurotransmitter systems. In the short run, this complex, fear-induced activation allows the …

GAD65 haplodeficiency conveys resilience in animal models of stress-induced psychopathology

I Müller, K Obata, G Richter-Levin… - Frontiers in Behavioral …, 2014 - frontiersin.org
GABAergic mechanisms are critically involved in the control of fear and anxiety, but their role
in the development of stress-induced psychopathologies, including post-traumatic stress …

Searching for non-genetic molecular and imaging PTSD risk and resilience markers: Systematic review of literature and design of the German Armed Forces PTSD …

U Schmidt, GD Willmund, F Holsboer, CT Wotjak… - …, 2015 - Elsevier
Biomarkers allowing the identification of individuals with an above average vulnerability or
resilience for posttraumatic stress disorder (PTSD) would especially serve populations at …

Posttraumatic stress disorder complicated by traumatic Brain Injury: a narrative review

SL Aita, KR Schuler, SL Isaak, NC Borgogna… - SN Comprehensive …, 2023 - Springer
We reviewed the phenomenology of Post-Traumatic Stress Disorder (PTSD) and Traumatic
Brain Injury (TBI), as well as the combined effects of PTSD+ TBI comorbidity on functional …

Plasma gamma-aminobutyric acid (GABA) levels and posttraumatic stress disorder symptoms in trauma-exposed women: a preliminary report

KA Arditte Hall, SE DeLane, GM Anderson… - …, 2021 - Springer
Rationale Aberrations in the stress response are associated with posttraumatic stress
disorder (PTSD) symptom development, maintenance, and severity. Gamma-aminobutyric …

Alcohol-exacerbates post-traumatic stress psychiatric behavior and its neuropathological sequalae in experimental mice: preventive effects of morin

B Ben-Azu, PEY Toloyai, A Adebesin, VO Ojiokor… - Alcohol, 2024 - Elsevier
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are very prevalent and
co-occurring. It is unclear how alcohol exacerbates PTSD predicaments owing to less …

[图书][B] Wiley concise guides to mental health: Posttraumatic stress disorder

A Cash - 2006 - books.google.com
The new, quick reference for understanding Posttraumatic Stress Disorder The Wiley
Concise Guides to Mental Health: Posttraumatic Stress Disorder uses clear, highly …

Rapid anti-PTSD-like activity of the TSPO agonist YL-IPA08: Emphasis on brain GABA, neurosteroids and HPA axis function

C Shang, Y Guo, JQ Yao, XX Fang, LJ Sun… - Behavioural brain …, 2020 - Elsevier
There is a serious need for fast-acting drugs to treat post-traumatic stress disorder (PTSD).
Our previous studies revealed that YL-IPA08, a novel small-molecule TSPO agonist, exerted …

Is plasma GABA level a biomarker of post-traumatic stress disorder (PTSD) severity? A preliminary study

M Trousselard, B Lefebvre, L Caillet, Y Andruetan… - Psychiatry …, 2016 - Elsevier
Objectives An increased reactivity to the environment is observed in Post-Traumatic Stress
Disorder (PTSD). It would be related to impairment of the Gamma Amino Butyric Acid …

Literature review and methodological considerations for understanding circulating risk biomarkers following trauma exposure

SD Linnstaedt, AS Zannas, SA McLean… - Molecular …, 2020 - nature.com
Exposure to traumatic events is common. While many individuals recover following trauma
exposure, a substantial subset develop adverse posttraumatic neuropsychiatric sequelae …