Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection.

MS Meltzer, DR Skillman, PJ Gomatos… - Annual review of …, 1990 - europepmc.org
We have presented evidence in this review for the following:(a) Macrophages are likely the
first cell infected by HIV. Recovery of HIV from macrophages has been documented in the …

Macrophages and the human immunodeficiency virus

MS Meltzer, DR Skillman, DL Hoover, BD Hanson… - Immunology today, 1990 - Elsevier
Mononuclear phagocytes are major participants in human immunodeficiency virus (HIV)
disease. These cells function as susceptible targets, persistent reservoirs for virus in tissue …

Human immunodeficiency virus and the brain: investigation of virus load and neuropathologic changes in pre-AIDS subjects

JE Bell, A Busuttil, JW Ironside, S Rebus… - Journal of Infectious …, 1993 - academic.oup.com
Brain tissue was examined for evidence of human immunodeficiency virus (HIV) infection in
23 intravenous drug users who died suddenly some years after seroconversion but while …

Epidural blood patch in the HIV-positive patient. Review of clinical experience. San Diego HIV Neurobehavioral Research Center.

DJ Tom, SJ Gulevich, HM Shapiro, RK Heaton… - …, 1992 - europepmc.org
To characterize the natural history of autologous epidural blood patch (EBP) in human
immunodeficiency virus (HIV)-seropositive patients, records from an ongoing longitudinal …

Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and …

MS Meltzer, M Nakamura, BD Hansen… - AIDS research and …, 1990 - liebertpub.com
Although macrophages are major targets for human immunodeficiency virus (HIV) infection
in vivo, study of HIV-macrophage interactions in vitro was hindered because many …

Rodent models for HIV-associated neurocognitive disorders

S Gorantla, L Poluektova, HE Gendelman - Trends in neurosciences, 2012 - cell.com
Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) reflect
the spectrum of neural impairments seen during chronic viral infection. Current research …

Regulation of tissue inhibitor of metalloproteinase‐1 by astrocytes: links to HIV‐1 dementia

R Suryadevara, S Holter, K Borgmann, R Persidsky… - Glia, 2003 - Wiley Online Library
The neuropathogenesis of HIV‐1‐associated dementia (HAD) revolves around the secretion
of toxic molecules from infected and immune‐competent mononuclear phagocytes …

Debate:“is increasing neuroinflammation beneficial for neural repair?”

KA Crutcher, HE Gendelman, J Kipnis… - Journal of Neuroimmune …, 2006 - Springer
The International Neural Regeneration Symposia began in 1985 and have been held
biennially since then. Dr. Roger Madison serves as the director of the symposium, which is …

Mononuclear phagocytes as targets, tissue reservoirs, and immunoregulatory cells in human immunodeficiency virus disease

MS Meltzer, HE Gendelman - Macrophage Biology and Activation, 1992 - Springer
Infection by the human immunodeficiency virus (HIV) initiates a slowly progressive
degenerative disease of the immune system termed the acquired immunodeficiency …

Nanoparticle based galectin-1 gene silencing, implications in methamphetamine regulation of HIV-1 infection in monocyte derived macrophages

JL Reynolds, WC Law, SD Mahajan… - Journal of Neuroimmune …, 2012 - Springer
Abstract Galectin-1, an adhesion molecule, is expressed in macrophages and implicated in
human immunodeficiency virus (HIV-1) viral adsorption. In this study, we investigated the …