[HTML][HTML] Stimuli-activatable nanomedicine meets cancer theranostics

H Li, Y Feng, Q Luo, Z Li, X Li, H Gan, Z Gu, Q Gong… - Theranostics, 2023 - ncbi.nlm.nih.gov
Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …

Recent progress in nanostructured smart drug delivery systems for cancer therapy: a review

MI Khan, MI Hossain, MK Hossain… - ACS Applied Bio …, 2022 - ACS Publications
Traditional treatment approaches for cancer involve intravenous chemotherapy or other
forms of drug delivery. These therapeutic measures suffer from several limitations such as …

Tumor‐microenvironment‐responsive cascade reactions by a cobalt‐single‐atom nanozyme for synergistic nanocatalytic chemotherapy

S Cai, J Liu, J Ding, Z Fu, H Li, Y Xiong… - Angewandte …, 2022 - Wiley Online Library
Nanocatalytic therapy, involving the nanozyme‐triggered production of reactive oxygen
species (ROS) in the tumor microenvironment (TME), has demonstrated potential in tumor …

Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance

W Wu, JL Klockow, M Zhang, F Lafortune… - Pharmacological …, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …

[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

[HTML][HTML] The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy

Y Shi, R van der Meel, X Chen, T Lammers - Theranostics, 2020 - ncbi.nlm.nih.gov
Following its discovery more than 30 years ago, the enhanced permeability and retention
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …

Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

[HTML][HTML] Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment

X Xu, C Liu, Y Wang, O Koivisto, J Zhou, Y Shu… - Advanced drug delivery …, 2021 - Elsevier
Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

[HTML][HTML] Recent advances in polysaccharides based biomaterials for drug delivery and tissue engineering applications

A Sood, A Gupta, G Agrawal - Carbohydrate Polymer Technologies and …, 2021 - Elsevier
In this paper, a spotlight is shown on polysaccharides based biomaterials which have
surfaced as a versatile platform for different biomedical applications including drug delivery …