Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

Over the last decade, researchers have discovered that a group of apparently unrelated
neurodegenerative disorders, such as Parkinson's disease, have remarkable cellular and …

Recent studies have firmly established that the etiology of autism includes both genetic and
environmental components. However, we are only just beginning to elucidate the …

GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the
central nervous system (CNS). Regulation of GABAAR trafficking and the control of their …

Depressive disorders have been shown to be highly influenced by environmental
pathogenic factors, some of which are believed to exert stress on human brain functioning …

Pain is a complex multidimensional experience encompassing sensory-discriminative,
affective-motivational and cognitive-emotional components mediated by different neural …

In fragile X syndrome (FX), the leading monogenic cause of autism, excessive neuronal
protein synthesis is a core pathophysiology; however, an overall increase in protein …

Ubiquitous expression of GABA type A receptors (GABAAR) in the central nervous system
establishes their central role in coordinating most aspects of neural function and …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with hallmark symptoms
including social deficits, communication deficits and repetitive behaviors. Accumulating …

Chronic inflammation during pregnancy (eg, preeclampsia, diabetes) is linked to increased
risk for offspring neurodevelopmental disorders such as autism spectrum disorder (ASD) …