Metastatic disease is the major cause of death from cancer, and immunotherapy and
chemotherapy have had limited success in reversing its progression. Data from mouse …

Solid tumors are initiated by genetic mutations in non-hematopoietic cells and progress into
invasive malignant tumors. This tumor progression often culminates in metastatic disease …

Background Distant metastasis resulting from vascular dissemination of cancer cells is the
primary cause of mortality from breast cancer. We have previously reported that E-selectin …

The regulation of mechanical properties is necessary for cell invasion into connective tissue
or intra-and extravasation through the endothelium of blood or lymph vessels. Cell invasion …

Quantitative elasticity imaging seeks to retrieve spatial maps of elastic moduli of tissue.
Unlike strain, which is commonly imaged in compression elastography, elastic moduli are …

The narrow slit between endothelial cells that line the microvessel wall is the principal
pathway for tumor cell extravasation to the surrounding tissue. To understand this crucial …

Our knowledge of the biology of solid cancer has greatly progressed during the last few
years, and many excellent reviews dealing with the various aspects of this biology have …

Chrysin, a flavonoid, has played a great role in the fields of anticancer, antibacterial, and
antiviral drug discovery. A large number of chrysin derivatives have been synthesized …

Quantification of mechanical properties of tissues, living cells, and cellular components is
crucial for the modeling of plant developmental processes such as mechanotransduction …

Cancer cell extravasation is a crucial step in cancer metastasis. However, many of the
mechanisms involved in this process are only now being elucidated. Thus, in the present …