Receptor-targeted dual pH-triggered intracellular protein transfer
M Lyu, M Yazdi, Y Lin, M Höhn… - ACS Biomaterials …, 2022 - ACS Publications
Protein therapeutics are of widespread interest due to their successful performance in the
current pharmaceutical and medical fields, even though their broad applications have been …
current pharmaceutical and medical fields, even though their broad applications have been …
Delivery of RNA to the Blood-Brain Barrier Endothelium Using Cationic Bicelles
J Cheng, L Wang, V Guttha, G Haugstad… - Pharmaceutics, 2023 - mdpi.com
Blood-brain barrier (BBB) dysfunction is prevalent in Alzheimer's disease and other
neurological disorders. Restoring normal BBB function through RNA therapy is a potential …
neurological disorders. Restoring normal BBB function through RNA therapy is a potential …
Materials nanoarchitectonics at dynamic interfaces: Structure formation and functional manipulation
K Ariga - Materials, 2024 - mdpi.com
The next step in nanotechnology is to establish a methodology to assemble new functional
materials based on the knowledge of nanotechnology. This task is undertaken by …
materials based on the knowledge of nanotechnology. This task is undertaken by …
CO-DELIVERY OF GLUTAMIC ACID-EXTENDED PEPTIDE ANTIGEN AND IMIDAZOQUINOLINE TLR7/8 AGONIST VIA IONIZABLE LIPID NANOPARTICLES …
T Ye, Z Zhong, F Cappellesso, K De Swarte, Y Chen… - Biomaterials, 2024 - Elsevier
Cancer vaccines aim at generating cytotoxic CD8+ T cells that kill cancer cells and confer
durable tumor regression. Hereto, CD8+ peptide epitopes should be presented by antigen …
durable tumor regression. Hereto, CD8+ peptide epitopes should be presented by antigen …
Elucidating Structural Configuration of Lipid Assemblies for mRNA Delivery Systems
The development of mRNA delivery systems utilizing lipid-based assemblies holds immense
potential for precise control of gene expression and targeted therapeutic interventions …
potential for precise control of gene expression and targeted therapeutic interventions …
Lipid Nanoparticle-Based Delivery System─ A Competing Place for mRNA Vaccines
X Zhang, Y Li, Z Zhou - ACS omega, 2024 - ACS Publications
mRNA, as one of the foci of biomedical research in the past decade, has become a
candidate vaccine solution for various infectious diseases and tumors and for regenerative …
candidate vaccine solution for various infectious diseases and tumors and for regenerative …
Nanoparticle platform comprising lipid-tailed pH-sensitive carbon dots with minimal drug loss
Herein, we synthesized a lipid-mimicking organic material (PCD_FA) that can surpass the
efficacy of lipid-based nanoparticles and demonstrated its potential as a delivery vehicle for …
efficacy of lipid-based nanoparticles and demonstrated its potential as a delivery vehicle for …
Confined Space Nanoarchitectonics for Dynamic Functions and Molecular Machines
K Ariga - Micromachines, 2024 - mdpi.com
Nanotechnology has advanced the techniques for elucidating phenomena at the atomic,
molecular, and nano-level. As a post nanotechnology concept, nanoarchitectonics has …
molecular, and nano-level. As a post nanotechnology concept, nanoarchitectonics has …
Lipid‐Based Nanoparticles
Lipid nanoparticles (LNPs) have gained significant attention in developing vaccines due to
their unique properties, including biocompatibility, biodegradability, and the ability to …
their unique properties, including biocompatibility, biodegradability, and the ability to …
Lipid membrane interface viewpoint: From viral entry to antiviral and vaccine development
Membrane-enveloped viruses are responsible for most viral pandemics in history, and more
effort is needed to advance broadly applicable countermeasures to mitigate the impact of …
effort is needed to advance broadly applicable countermeasures to mitigate the impact of …