Orofacial pain remains a significant health issue in the United States. Pain originating from
the orofacial region can be composed of a complex array of unique target tissue that …

Skeletal diseases impose a considerable burden on society. The clinical and tissue-
engineering therapies applied to alleviate such diseases frequently result in complications …

Aims: The acceleration of osteoarthritis (OA) development by chondrocytes undergoing
ferroptosis has been observed. Plumbagin (PLB), known for its potent antioxidant and anti …

Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions
that affect temporomandibular joints, masticatory muscles, and associated structures …

The functionalization of bone substitutes with exosomes appears to be a promising
technique to enhance bone tissue formation. This study investigates the potential of …

TMJOA as a progressive degenerative disease of the TMJ, is featured as enhanced
inflammation, chondrocyte apoptosis, ECM degradation and subchondral bone remodeling …

BNTA is known to have a therapeutic effect on knee osteoarthritis and inflammatory
osteoclastogenesis. However, the protective effect of BNTA regarding temporomandibular …

Temporomandibular joint (TMJ) osteoarthritis causes fibrocartilage damage to the TMJ disc
and mandibular condyle, resulting in local pain and functional impairment that further …

Temporomandibular joint osteoarthritis (TMJOA) is a degenerative ailment that causes slow
cartilage degeneration, aberrant bone remodeling, and persistent discomfort, leading to a …

The aim of the second edition of this Special Issue was to collect both review and original
research articles that investigate and elucidate the possible therapeutic role of perinatal …