[HTML][HTML] Antimicrobial peptides: classification, design, application and research progress in multiple fields

Y Huan, Q Kong, H Mou, H Yi - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and
they are an important part of the innate immune system of different organisms. AMPs have a …

The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Chemically modified and conjugated antimicrobial peptides against superbugs

W Li, F Separovic, NM O'Brien-Simpson… - Chemical Society …, 2021 - pubs.rsc.org
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

[HTML][HTML] Antimicrobial peptides and proteins: from nature's reservoir to the laboratory and beyond

T Sarkar, M Chetia, S Chatterjee - Frontiers in Chemistry, 2021 - frontiersin.org
Rapid rise of antimicrobial resistance against conventional antimicrobials, resurgence of
multidrug resistant microbes and the slowdown in the development of new classes of …

[HTML][HTML] D-and unnatural amino acid substituted antimicrobial peptides with improved proteolytic resistance and their proteolytic degradation characteristics

J Lu, H Xu, J Xia, J Ma, J Xu, Y Li, J Feng - Frontiers in Microbiology, 2020 - frontiersin.org
The transition of antimicrobial peptides (AMPs) from the laboratory to market has been
severely hindered by their instability toward proteases in biological systems. In the present …

Antimicrobial peptides: from design to clinical application

C Zhang, M Yang - Antibiotics, 2022 - mdpi.com
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

Strategies for improving antimicrobial peptide production

S Deo, KL Turton, T Kainth, A Kumar, HJ Wieden - Biotechnology advances, 2022 - Elsevier
Antimicrobial peptides (AMPs) found in a wide range of animal, insect, and plant species are
host defense peptides forming an integral part of their innate immunity. Although the exact …

Embracing the era of antimicrobial peptides with marine organisms

P Chen, T Ye, C Li, P Praveen, Z Hu, W Li… - Natural Product …, 2024 - pubs.rsc.org
Covering: 2018 to Jun of 2023 The efficiency of traditional antibiotics has been undermined
by the proliferation of antibiotic-resistant pathogenic microorganisms, necessitating the …

Identification of single amino acid chiral and positional isomers using an electrostatically asymmetric nanopore

J Wang, JD Prajapati, F Gao, YL Ying… - Journal of the …, 2022 - ACS Publications
Chirality is essential in nearly all biological organizations and chemical reactions but is
rarely considered due to technical limitations in identifying L/D isomerization. Using OmpF, a …