[HTML][HTML] Recent progress of lipid nanoparticles-based lipophilic drug delivery: focus on surface modifications

Y Seo, H Lim, H Park, J Yu, J An, HY Yoo, T Lee - Pharmaceutics, 2023 - mdpi.com
Numerous drugs have emerged to treat various diseases, such as COVID-19, cancer, and
protect human health. Approximately 40% of them are lipophilic and are used for treating …

Effects of food formulation on bioavailability of phytosterols: phytosterol structures, delivery carriers, and food matrices

T Wang, C Ma, Y Hu, S Guo, G Bai, G Yang, R Yang - Food & Function, 2023 - pubs.rsc.org
Daily intake of phytosterols (PSs) as a diet supplement can lower blood-cholesterol levels
and reduce the risks of cardiovascular diseases. However, the high crystallinity, low water …

Mechanism underlying joint loading and controlled release of β-carotene and curcumin by octenylsuccinated Gastrodia elata starch aggregates

Z Wu, X Tang, S Liu, S Li, X Zhao, Y Wang… - Food Research …, 2023 - Elsevier
This study aimed to fabricate a novel codelivery system to simultaneously load β-carotene
and curcumin in a controlled and synergistic manner. We hypothesized that the aggregates …

Guar gum series affect nanostructured lipid carriers via electrostatic assembly or steric hindrance: Improving their oral delivery for phytosterols

SJ Guo, XD Wang, YX Ma, YY Hu, RN Yang… - International journal of …, 2023 - Elsevier
Surface modification of nanostructured lipid carriers (NLCs) can be an effective way to
improve their oral delivery for active ingredients. In this study, four type of guar gum series …

Characterization and stability of solid lipid nanoparticles produced from different fully hydrogenated oils

MA Stahl, FL Lüdtke, R Grimaldi, ML Gigante… - Food Research …, 2024 - Elsevier
The use of lipids from conventional oils and fats to produce solid lipid nanoparticles (SLN)
attracting interest from the food industry, since due their varying compositions directly affects …

Tackling the cytokine storm using advanced drug delivery in allergic airway disease

VK Patel, S Vishwas, R Kumar, G De Rubis… - Journal of Drug Delivery …, 2023 - Elsevier
Asthma is one of the leading causes of mortality worldwide presenting a huge socio-
economic burden with rising morbidity and mortality rates. It is a chronic inflammatory airway …

Physicochemical and in vitro digestion properties of curcumin-loaded solid lipid nanoparticles with different solid lipids and emulsifiers

Y Yu, D Chen, YY Lee, N Chen, Y Wang, C Qiu - Foods, 2023 - mdpi.com
Curcumin-loaded solid lipid nanoparticles (Cur-SLN) were prepared using medium-and
long chain diacylglycerol (MLCD) or glycerol tripalmitate (TP) as lipid matrix and three kinds …

A notable impact of lipid matrices on cholesterol bioaccessibility from phytosterols-loaded nanostructured lipid carriers during in vitro intestinal digestion

S Guo, C Ma, Y Hu, Z Song, T Wang, R Yang - Food Bioscience, 2023 - Elsevier
Encapsulation of phytosterols in nanostructured lipid carriers (NLCs) is an effective
approach to improve their physicochemical properties, but the interaction of phytosterols in …

Critical review in designing plant-based anticancer nanoparticles against hepatocellular carcinoma

A Basu, T Namporn, P Ruenraroengsak - Pharmaceutics, 2023 - mdpi.com
Hepatocellular carcinoma (HCC), accounting for 85% of liver cancer cases, continues to be
the third leading cause of cancer-related deaths worldwide. Although various forms of …

[HTML][HTML] Impact of extrusion processing on bioactive compound enriched plant-based extrudates: A comprehensive study and optimization using RSM and ANN-GA

M Pavani, P Singha, DT Rajamanickam, SK Singh - Future Foods, 2024 - Elsevier
The present study aimed to investigate the influence of extrusion process parameters,
specifically screw speed (300 to 500 rpm) and temperature (130 to 150° C) on the stability of …