Dynamic interactions in the tumor niche: how the cross-talk between CAFs and the tumor microenvironment impacts resistance to therapy

O Piwocka, I Piotrowski, WM Suchorska… - Frontiers in Molecular …, 2024 - frontiersin.org
The tumor microenvironment (TME) is a complex ecosystem of cells, signaling molecules,
and extracellular matrix components that profoundly influence cancer progression. Among …

Exosomes: a Cutting-Edge Theranostics Tool for Oral Cancer

K Kalele, S Nyahatkar, D Mirgh… - ACS Applied Bio …, 2024 - ACS Publications
Exosomes are a subpopulation of extracellular vesicles (EVs) secreted by cells. In cancer,
they are key cellular messengers during cancer development and progression. Tumor …

Oral tumor heterogeneity, its implications for patient monitoring and designing anti-cancer strategies

R Mishra - Pathology-Research and Practice, 2023 - Elsevier
Oral cancer tumors occur in the mouth and are mainly derived from oral mucosa linings. It is
one of the most common and fatal malignant diseases worldwide. The intratumor …

Understanding exosomes: Part 3—therapeutic+ diagnostic potential in dentistry

RJ Miron, NE Estrin, A Sculean… - Periodontology 2000, 2024 - Wiley Online Library
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with the ability to communicate with other tissues and cell types over long distances. Their …

Application of exosomes in tumor immunity: recent progresses

H Qiu, J Liang, G Yang, Z Xie, Z Wang… - Frontiers in Cell and …, 2024 - frontiersin.org
Exosomes are small extracellular vesicles secreted by cells, ranging in size from 30 to 150
nm. They contain proteins, nucleic acids, lipids, and other bioactive molecules, which play a …

The hidden messengers: cancer associated fibroblasts—derived exosomal miRNAs as key regulators of cancer malignancy

Z Gou, J Li, J Liu, N Yang - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Cancer-associated fibroblasts (CAFs), a class of stromal cells in the tumor microenvironment
(TME), play a key role in controlling cancer cell invasion and metastasis, immune evasion …

Role of exosomes in the communication and treatment between OSCC and normal cells

X Ma, R Yang, H Li, X Zhang, X Zhang, X Li - Heliyon, 2024 - cell.com
Oral squamous cell carcinoma (OSCC) is a prevalent cancer that needs new therapeutic
targets due to the poor postoperative prognosis in patients. Exosomes are currently one of …