Recent advancements in the creation of artificial extra base pairs (unnatural base pairs,
UBPs) are opening the door to a new research area, xenobiology, and genetic alphabet …

Viral respiratory tract infections are common and usually selflimited illnesses. For patients at
risk of asthma, or with existing asthma, viral respiratory tract infections can have a profound …

Background Research has underscored the effects of exposure and sensitization to
allergens on the severity of asthma in inner-city children. It has also revealed the limitations …

Rationale: Virus-induced wheezing episodes in infancy often precede the development of
asthma. Whether infections with specific viral pathogens confer differential future asthma risk …

Background Early life rhinovirus (RV) wheezing illnesses and aeroallergen sensitization
increase the risk of asthma at school age. Whether these remain risk factors for the …

The ideal clinical diagnostic system should deliver rapid, sensitive, specific and reproducible
results while minimizing the requirements for specialized laboratory facilities and skilled …

Despite increased understanding of how viral infection is involved in asthma exacerbations,
it is less clear which viruses are involved and to what extent they contribute to asthma …

Background Detection of either viral or bacterial pathogens is associated with wheezing in
children; however, the influence of both bacteria and viruses on illness symptoms has not …

The introduction of in vitro nucleic acid amplification techniques, led by real-time PCR, into
the clinical microbiology laboratory has transformed the laboratory detection of viruses and …

Background Recent studies suggest that humans exhale fine particles during tidal breathing
but little is known of their composition, particularly during infection. Methodology/Principal …