[HTML][HTML] Narrative review of metabolomics in cardiovascular disease

J Müller, T Bertsch, J Volke, A Schmid… - Journal of Thoracic …, 2021 - ncbi.nlm.nih.gov
Cardiovascular diseases are accompanied by disorders in the cardiac metabolism.
Furthermore, comorbidities often associated with cardiovascular disease can alter systemic …

[HTML][HTML] Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino …

Y Lee, AHJ Kim, E Kim, SH Lee, KS Yu, IJ Jang… - Diabetes Research and …, 2021 - Elsevier
Aims Although metformin has been reported to affect the gut microbiome, the mechanism
has not been fully determined. We explained the potential underlying mechanisms of …

A metabolomics approach to evaluate the effect of lyophilization versus oven drying on the chemical composition of plant extracts

NA ElNaker, M Daou, MA Ochsenkühn, SA Amin… - Scientific reports, 2021 - nature.com
Lyophilization is the “gold standard” for drying plant extracts, which is important in
preserving their quality and extending their shelf-life. Compared to other methods of drying …

Gas chromatography-mass spectrometry-based untargeted metabolomics reveals metabolic perturbations in medullary thyroid carcinoma

MG Jajin, R Abooshahab, K Hooshmand, A Moradi… - Scientific Reports, 2022 - nature.com
Medullary thyroid cancer (MTC) is a rare tumor that arises from parafollicular cells within the
thyroid gland. The molecular mechanism underlying MTC has not yet been fully understood …

Integrating animal health and stress assessment tools using the green-lipped mussel Perna canaliculus as a case study

NJ Delorme, L Venter, A Rolton, JA Ericson - Journal of Shellfish Research, 2021 - BioOne
Marine organisms are constantly exposed to stress, such as changes in seawater
temperature, which may elicit biochemical, molecular, and physiological changes. In the …

Kefir metabolites in a fly model for Alzheimer's disease

LL Batista, SM Malta, HC Guerra Silva, LDF Borges… - Scientific reports, 2021 - nature.com
Alzheimer's Disease (AD) is the most common cause of dementia among elderly individuals
worldwide, leading to a strong motor-cognitive decline and consequent emotional distress …

Novel strategies for clinical investigation and biomarker discovery: a guide to applied metabolomics

G Carneiro, AL Radcenco, J Evaristo… - … molecular biology and …, 2019 - degruyter.com
Metabolomics is an emerging technology that is increasing both in basic science and in
human applications, providing a physiological snapshot. It has been highlighted as one of …

Metabolomics meets lipidomics: Assessing the small molecule component of metabolism

H Gallart‐Ayala, T Teav, J Ivanisevic - BioEssays, 2020 - Wiley Online Library
Metabolomics, including lipidomics, is emerging as a quantitative biology approach for the
assessment of energy flow through metabolism and information flow through metabolic …

Integrated LC–MS and GC–MS-based metabolomics reveal the effects of plant competition on the rye metabolome

H Hazrati, P Kudsk, L Ding, H Uthe… - Journal of Agricultural …, 2022 - ACS Publications
Plants compete with their neighbors about the limited resources available to them. Plants
under induced stress resulting from competition may alter their metabolome to increase their …

Application of untargeted volatile profiling and data driven approaches in wine flavoromics research

M Pérez-Jiménez, E Sherman, MA Pozo-Bayón… - Food Research …, 2021 - Elsevier
Traditional flavor chemistry research usually makes use of targeted approaches by focusing
on the detection and quantification of key flavor active metabolites that are present in food …