[HTML][HTML] Novel PET imaging of inflammatory targets and cells for the diagnosis and monitoring of giant cell arteritis and polymyalgia rheumatica

KSM van der Geest, M Sandovici, PH Nienhuis… - Frontiers in …, 2022 - frontiersin.org
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two interrelated
inflammatory diseases affecting patients above 50 years of age. Patients with GCA suffer …

PSMA targeted molecular imaging and radioligand therapy for prostate cancer: optimal patient and treatment issues

S Hoshi, K Yaginuma, S Meguro, A Onagi… - Current …, 2023 - mdpi.com
Theranostics (therapy+ diagnosis) targeting prostate-specific membrane antigen (PSMA) is
an emerging therapeutic modality that could alter treatment strategies for prostate cancer …

Recent developments in PET and SPECT radiotracers as radiopharmaceuticals for hypoxia tumors

AT Nguyen, HK Kim - Pharmaceutics, 2023 - mdpi.com
Hypoxia, a deficiency in the levels of oxygen, is a common feature of most solid tumors and
induces many characteristics of cancer. Hypoxia is associated with metastases and strong …

An Overview of In Vitro Assays of 64Cu-, 68Ga-, 125I-, and 99mTc-Labelled Radiopharmaceuticals Using Radiometric Counters in the Era of Radiotheranostics

V Benfante, A Stefano, M Ali, R Laudicella, W Arancio… - Diagnostics, 2023 - mdpi.com
Radionuclides are unstable isotopes that mainly emit alpha (α), beta (β) or gamma (γ)
radiation through radiation decay. Therefore, they are used in the biomedical field to label …

Microfluidic synthesis of radiotracers: recent developments and commercialization prospects

M Mc Veigh, LM Bellan - Lab on a Chip, 2024 - pubs.rsc.org
Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …

Phase I Randomized Trial of 17O‐Labeled Water: Safety and Feasibility Study of Indirect Proton MRI for the Evaluation of Cerebral Water Dynamics

T Harada, K Kudo, H Kameda, R Sato… - Journal of Magnetic …, 2022 - Wiley Online Library
Background 17O‐labeled water (PSO17) is a contrast agent developed to measure brain
water dynamics and cerebral blood flow. Purpose To evaluate the safety and feasibility of …

Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source

J Peñas, A Alejo, A Bembibre, JI Apiñaniz… - Scientific Reports, 2024 - nature.com
Most advanced medical imaging techniques, such as positron-emission tomography (PET),
require tracers that are produced in conventional particle accelerators. This paper focuses …

Short life fission products extracted from molten salt reactor fuel for radiopharmaceutical applications.

C Degueldre, J Findlay, D Cheneler, S Sardar… - Applied Radiation and …, 2024 - Elsevier
This work studies the potential of using short life fission product (A Fp) radioisotopes eg 82
Br, 86 Rb,(90 Sr)-90m Y,(99 Mo)-99m Tc, 103 Ru-103m Rh, 111 Ag, 127 Sb-127 (m) Te, 126 …

Early diagnosis and staging of paraquat-induced pulmonary fibrosis using [18F]F-FAPI-42 PET/CT imaging

D Zhang, Y Shi, J Kong, N Chen, G Li, M Wang… - EJNMMI research, 2024 - Springer
Background Paraquat (PQ)-induced pulmonary fibrosis poses a significant medical
challenge due to limited treatment options and high mortality rates. Consequently, there is …

Performance evaluation of Gallium-68 radiopharmaceuticals production using liquid target PETtrace 800 cyclotron

Z Ashhar, MFA Fadzil, ZM Safee, F Aziz… - Applied Radiation and …, 2024 - Elsevier
Due to increased demand, cyclotron has an expanding role in producing Gallium-68 (68 Ga)
radiopharmaceuticals using solid and liquid targets. Though the liquid target produces lower …