Thymic involution and immune reconstitution

HE Lynch, GL Goldberg, A Chidgey… - Trends in …, 2009 - cell.com
Chronic thymus involution associated with aging results in less efficient T-cell development
and decreased emigration of naïve T cells to the periphery. Thymic decline in the aged is …

Immune reconstitution after hematopoietic cell transplantation

M Bosch, FM Khan, J Storek - Current opinion in hematology, 2012 - journals.lww.com
Immune reconstitution after hematopoietic cell transplantati... : Current Opinion in
Hematology Immune reconstitution after hematopoietic cell transplantation : Current …

[HTML][HTML] Guidelines for preventing infectious complications among hematopoietic cell transplant recipients: a global perspective

M Tomblyn, T Chiller, H Einsele, R Gress… - Bone marrow …, 2009 - nature.com
Guidelines for preventing infectious complications among hematopoietic cell transplant
recipients: a global perspective | Bone Marrow Transplantation Skip to main content Thank you …

[HTML][HTML] Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM …

D Rea, G Henry, Z Khaznadar, G Etienne… - …, 2017 - ncbi.nlm.nih.gov
Despite persistence of leukemic stem cells, patients with chronic myeloid leukemia who
achieve and maintain deep molecular responses may successfully stop the tyrosine kinase …

NK cells and T cells cooperate during the clinical course of colorectal cancer

G Sconocchia, S Eppenberger, GC Spagnoli… - …, 2014 - Taylor & Francis
Recent evidence suggests that natural killer (NK) cells are typically defective in infiltrating
solid tumors, with the exception of gastrointestinal stromal tumors (GIST). Interestingly …

Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute …

BN Savani, S Mielke, S Adams, M Uribe, K Rezvani… - Leukemia, 2007 - nature.com
Natural killer (NK) cells are the first lymphocytes to recover after allogeneic stem cell
transplantation (SCT) and can exert powerful graft-versus-leukemia (GVL) effects …

[HTML][HTML] The microbiome and hematopoietic cell transplantation: past, present, and future

TM Andermann, JU Peled, C Ho, P Reddy… - Biology of Blood and …, 2018 - Elsevier
Highlights•Microbiome alterations are associated with infection, GVHD, and other adverse
transplant outcomes.•“Multiomic” technologies may better identify clinically actionable …

[HTML][HTML] Ex vivo T-cell depletion in allogeneic hematopoietic stem cell transplant: past, present and future

A Saad, LS Lamb - Bone marrow transplantation, 2017 - nature.com
The most common cause of post-transplant mortality in patients with hematological
malignancy is relapse, followed by GvHD, infections, organ toxicity and second malignancy …

Immune reconstitution and implications for immunotherapy following hematopoeitic stem cell transplantation

KM Williams, RE Gress - Allogeneic stem cell transplantation, 2010 - Springer
The innate immune system comprises a collection of cells that recognize and eradicate
pathogens or aberrant cells without priming or antigen presentation. Natural killer cells …

[HTML][HTML] Lymphocyte subset recovery and outcome after autologous hematopoietic stem cell transplantation for plasma cell myeloma

J Rueff, M Medinger, D Heim, J Passweg… - Biology of Blood and …, 2014 - Elsevier
Rapid immune reconstitution—particularly of natural killer cells (NK cells)—after allogeneic
hematopoietic stem cell transplantation (HSCT) is associated with protection from relapse …