[PDF][PDF] Angiogenesis and vascular functions in modulation of obesity, adipose metabolism, and insulin sensitivity

Y Cao - Cell metabolism, 2013 - cell.com
White and brown adipose tissues are hypervascularized and the adipose vasculature
displays phenotypic and functional plasticity to coordinate with metabolic demands of …

Physiological changes and pathological pain associated with sedentary lifestyle-induced body systems fat accumulation and their modulation by physical exercise

E Verdú, J Homs, P Boadas-Vaello - International journal of …, 2021 - mdpi.com
A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …

Enhanced oxygen supply improves islet viability in a new bioartificial pancreas

U Barkai, GC Weir, CK Colton, B Ludwig… - Cell …, 2013 - journals.sagepub.com
The current epidemic of diabetes with its overwhelming burden on our healthcare system
requires better therapeutic strategies. Here we present a promising novel approach for a …

Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist

B Ludwig, A Rotem, J Schmid… - Proceedings of the …, 2012 - National Acad Sciences
Islet transplantation is a feasible therapeutic alternative for metabolically labile patients with
type 1 diabetes. The primary therapeutic target is stable glycemic control and prevention of …

3D printed vascularized device for subcutaneous transplantation of human islets

M Farina, A Ballerini, DW Fraga, E Nicolov… - Biotechnology …, 2017 - Wiley Online Library
Transplantation of pancreatic islets or stem cell derived insulin secreting cells is an attractive
treatment strategy for diabetes. However, islet transplantation is associated with several …

Isolation, characterization and potential role in beta cell-endothelium cross-talk of extracellular vesicles released from human pancreatic islets

F Figliolini, V Cantaluppi, M De Lena, S Beltramo… - PloS one, 2014 - journals.plos.org
The cross-talk between beta cells and endothelium plays a key role in islet physiopathology
and in the revascularization process after islet transplantation. However, the molecular …

The benefits of physical exercise for the health of the pancreatic β‐cell: a review of the evidence

M Curran, MT Drayson, RC Andrews… - Experimental …, 2020 - Wiley Online Library
New Findings What is the topic of this review? This review discusses the evidence of the
benefits of exercise training for β‐cell health through improvements in function, proliferation …

Variation in normal range thyroid function affects serum cholesterol levels, blood pressure, and type 2 diabetes risk: a mendelian randomization study

A Kuś, E Marouli, F Del Greco M, L Chaker… - Thyroid, 2021 - liebertpub.com
Background: Observational studies have demonstrated that variation in normal range thyroid
function is associated with major cardiovascular risk factors, including dyslipidemia …

Generation of insulin‐producing cells from human adipose‐derived mesenchymal stem cells on PVA scaffold by optimized differentiation protocol

SE Enderami, M Soleimani, Y Mortazavi… - Journal of cellular …, 2018 - Wiley Online Library
The studies have been done on patient‐specific human adipose‐derived from mesenchymal
stem cells (hADSCs) like a series of autologous growth factors and nanofibrous scaffolds …

[HTML][HTML] Intra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation

S Narayanan, G Loganathan… - World journal of …, 2017 - ncbi.nlm.nih.gov
The intra-islet microvasculature is a critical interface between the blood and islet endocrine
cells governing a number of cellular and pathophysiological processes associated with the …