Targeting tumour immunosuppressive microenvironment is a crucial strategy in
immunotherapy. However, the critical role of the tumour lymph node (LN) immune …

Nowadays, the photothermal therapy (PTT) has received widespread attention and research
by rapidly killing tumors with local high temperature. However, due to the irregular edges of …

Abstract Purpose The claudin 18.2 (CLDN18. 2) antigen is frequently expressed in
malignant tumors, including pancreatic ductal adenocarcinoma (PDAC). Although CLDN18 …

Immunotherapy holds great promise for the treatment of aggressive and metastatic cancers;
however, currently available immunotherapeutics, such as immune checkpoint blockade …

Although immunotherapy has revolutionized oncotherapy, only≈ 15% of head and neck
squamous cell carcinoma (HNSCC) patients benefit from the current therapies. An …

DNA-damaging treatments such as radiotherapy (RT) have become promising to improve
the efficacy of immune checkpoint inhibitors by enhancing tumor immunogenicity. However …

Cancer immunotherapy is restricted to immune resistance caused by immunosuppressive
tumor microenvironment. Pyroptosis involved in antitumor immunotherapy as a new …

Context Therapies based on immune checkpoint inhibitors (ICIs) are transforming the
treatment landscape of urologic oncology. Nevertheless, an exhaustive overview of the …

Humans possess abundant amounts of microorganisms, including bacteria, fungi, viruses,
and archaea, in their gut. Patients with nonalcoholic fatty liver disease (NAFLD) exhibit …

Immunotherapy is a promising approach for treating metastatic breast cancer (MBC), offering
new possibilities for therapy. While checkpoint inhibitors have shown great progress in the …