The nitric oxide (NO) and cyclooxygenase (COX) pathways share a number of similarities.
Nitric oxide is the mediator generated from the NO synthase (NOS) pathway, and COX …

Colorectal cancer (CRC) is the third most diagnosed malignancy and the second leading
cause of cancer-related deaths worldwide. Locally advanced and metastatic disease exhibit …

Dietary polyphenols have been found to possess preventive and therapeutic potential
against several types of cancers. We investigated the effect of ellagic acid on colon cancer …

This study evaluated the hypothesis that untreated and irradiated grapefruit as well as the
isolated citrus compounds naringin and limonin would protect against azoxymethane (AOM) …

Epithelial-cadherin (E-cadherin) is a master organizer of the epithelial phenotype. Its
function is regulated in part by p120-catenin (referred to herein as p120), a cytoplasmic …

Epidemiological evidence suggests that a diet abundant in fruits and vegetables may protect
against colon cancer. Bioactive compounds, including flavonoids and limonoids, have been …

Colorectal cancer (CRC) results from the accumulation of both genetic and epigenetic
alterations of the genome. However, also the formation of an inflammatory milieu plays a …

Background Colorectal cancer is the third most malignant cancer worldwide. Despite novel
treatment options, the incidence and mortality rates of colon cancer continue to increase in …

Colorectal cancer is the second leading cause of cancer-related deaths in the United States.
Recent studies prove that though chemotherapeutic agents are being used for the treatment …

The human bowel contains a large and dynamic bacterial population that is not only
essential for intestinal health, but also critical for the development of diseases such as …