Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells

Z Cao, LZ Liu, DA Dixon, JZ Zheng, B Chandran… - Cellular signalling, 2007 - Elsevier
Elevated levels of insulin-like growth factor-I (IGF-I) are associated with ovarian
carcinogenesis and progression. However, the molecular mechanisms by which IGF-I …

Prospective Study of Urinary Prostaglandin E2 Metabolite and Colorectal Cancer Risk

Q Cai, YT Gao, WH Chow, XO Shu, G Yang… - Journal of Clinical …, 2006 - ascopubs.org
Purpose Overexpression of cyclooxygenase-2 (COX-2) has been shown to play a major role
in colorectal cancer pathogenesis. However, no human study has directly investigated …

EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways

S Donnini, F Finetti, R Solito, E Terzuoli… - The FASEB …, 2007 - Wiley Online Library
In squamous cell carcinoma, the levels of nitric oxide (NO) derived from inducible NO
synthase (iNOS) and prostaglandin E2 (PGE2) derived from cyclooxygenase‐2 (COX‐2) …

[HTML][HTML] The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer

H Gungor, N Ilhan, H Eroksuz - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Colorectal cancer (CRC) is an important cause of cancer-related deaths worldwide. Early
diagnosis and treatment of CRCs are of importance for improving the survival. In the present …

[PDF][PDF] Eecs Reduces Inflammation and Cell Proliferation In Rat Colon Carchnogenesis

MMP Demarzo, LV Martins, CR Fernandes… - 2008 - academia.edu
ABSTRACT DEMARZO, MM, LV MARTINS, CR FERNANDES, FA HERRERO, SE PEREZ, A.
TURATTI, and SB GARCIA. Exercise Reduces Inflammation and Cell Proliferation in Rat …

Correlation of E-cadherin, VEGF, COX-2 expression to prognostic parameters in papillary thyroid carcinoma

H Erdem, C Gündogdu, S Şipal - Experimental and molecular pathology, 2011 - Elsevier
Thyroid cancer represents approximately 1% of all human malignancies. papillary thyroid
carcinoma (PTC) is the most common malignant tumor of the thyroid gland, accounting for …

[HTML][HTML] Role of urinary biomarkers in the diagnosis of adenoma and colorectal cancer: a systematic review and meta-analysis

E Altobelli, PM Angeletti, G Latella - Journal of Cancer, 2016 - ncbi.nlm.nih.gov
The growing interest in enhancing and spreading colorectal cancer (CRC) screening has
been stimulating the exploration of novel biomarkers with greater sensitivity and specificity …

In vitro studies on the inhibition of colon cancer by butyrate and carnitine

MJ Roy, S Dionne, G Marx, I Qureshi, D Sarma, E Levy… - Nutrition, 2009 - Elsevier
OBJECTIVE: Epidemiologic studies support an association between diet and the incidence
of colorectal cancer. Butyrate, a short-chain fatty acid present in dietary fiber and dairy …

Cyclooxygenase-2: how good is it as a target for cancer chemoprevention?

MA Hull - European Journal of Cancer, 2005 - Elsevier
There is now substantial evidence for a role for cyclooxygenase-2 (COX-2)-mediated
prostaglandin (PG) signalling during carcinogenesis in a number of tissues and selective …

Dendritic cell infiltration pattern along the colorectal adenoma‐carcinoma sequence

A Yuan, SE Steigen, R Goll, B Vonen, A Husbekk… - Apmis, 2008 - Wiley Online Library
We have previously reported that the dendritic cell (DC) functional index cytokine interleukin‐
12 was significantly decreased in colorectal carcinoma (CRC) tissues. In this study, the DC …