Purpose: It has been extensively documented that the cyclooxygenase inducible form and
15-lipoxygenase are implicated in colorectal carcinogenesis. Nonetheless, the role of other …

Obesity is rapidly becoming a global phenomenon. This is more than a cosmetic issue as
obesity is associated with several life-threatening diseases, including colon cancer. Insulin …

Increased epithelial cell expression of the cyclooxgenase-2 (COX-2) enzyme is a
characteristic event of both inflammatory bowel disease and colon cancer. We here report …

Background and aim: The production of prostaglandins is regulated by cyclo-oxygenases
(COXs), which also have a role in tumour development and progression in various …

Background The purpose of this study was to explore the effects of sodium butyrate (NaB),
grape seed proanthocyanidin extract (GSPE), or their combination against …

Abstract Prostaglandin E2 (PGE2) has been shown to promote the development of murine
skin tumors. EP1 is 1 of the 4 PGE2 G‐protein‐coupled membrane receptors expressed by …

Cholangiocarcinoma (CCA) occurs frequently in primary sclerosing cholangitis (PSC).
Cyclooxygenase-2 (COX-2) and microsomal prostaglandin E synthase-1 (mPGES-1) …

The production of prostaglandins is regulated by cyclooxygenases (COXs), which also have
a role in tumour development and progression in various human malignancies, including …

Colorectal cancer is one of the most commonly diagnosed cancers and cause of cancer‐
related deaths worldwide. Studies have demonstrated that patient outcome is substantially …

目的: 研究环氧合酶(COX-2) 在结肠黏膜, 结肠腺瘤性息肉以及结肠癌中的表达, 并探讨COX-2
与结肠癌和结肠腺瘤性息肉之间的关系. 方法: 随机续贯选择结肠腺瘤性息肉患者30 例 …