I. Introduction C HORIONIC gonadotropin (CG) is a placental hormone that maintains the
corpus luteum of pregnancy. Because CG is expressed at high levels soon after fertilization …

The demonstration in 1927, by Ascheim and Zondek, of a substance with gonadotropic
activity in the urine of pregnant women marked the beginning of the endocrine evaluation of …

Abstract Analysis of published series indicates that, irrespective of the method of data
collection, close agreement exists on empirically derived incidences of spontaneous …

HCG or human pituitary LH was administered to normal women during the luteal phase of
the menstrual cycle. Functional activity of the corpora lutea was assessed by measurements …

Hypophysectomy, at any stage of pregnancy, interrupted gestation in the hamster. Pituitary
removal at day 1, 4 or 8 of pregnancy resulted in rapid regression of the corpus luteum (CL) …

Abstract Concentrations of Estradiol (E 2), progesterone (P), 17-hydroxyprogesterone (17-
OHP), follicle-stimulating hormone (FSH), luteinizing hormone-human chorionic …

Data obtained from immunologic and biologic assays of trophoblast, pituitaries, urine, and
sera of pregnant women demonstrate a similar pattern of production and excretion of human …

The ability of daily oxytocin injections to inhibit the growth of the corpus luteum and cause
precocious estrus in the bovine was used as a tool to test the luteotropic properties of …

Human chorionic gonadotropin was administered intramuscularly in an open study of 32
women whose last three pregnancies had ended in spontaneous abortion. An initial dosage …

The β subunit of human chorionic gonadotropin (CGβ) is encoded by a cluster of six genes,
which have developed through gene duplication from an ancestral LHβ gene. Despite …