Serum albumin, commonly recognized as a predominant major plasma protein, is
ubiquitously distributed among vertebrates, demonstrating versatility and widespread …

Albumin has shown remarkable promise as a natural drug carrier by improving
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …

Amino acids are natural compounds that can be safely used in pharmaceutical applications.
Considering the great interest in the amino acids used in the pharmaceutical industry, this …

Physicochemical characterization is a crucial step for the successful development of solid
dispersions, including the determination of drug crystallinity and molecular interactions …

As a functional polyphenolic compound, curcumin (CUR) has limited application due to its
low solubility and bioavailability. In this work, curcumin loaded micelles self-assembled from …

Background Leuprolide (LEU), a synthetic nonapeptide analog of naturally occurring
gonadotropin-releasing hormone (GnRH), could exert a direct inhibitory activity on the …

The objective of this study was to evaluate the effectiveness of organ-on-chip system
investigating simultaneous cellular efficacy and real-time reactive oxygen species (ROS) …

Applications of pea protein in the food industry have been greatly restricted by its poor
functional properties. In order to solve this problem, a novel technique combining enzymatic …

7-Ethyl-10-hydroxyl camptothecin (SN38), a semisynthetic derivative of camptothecin,
exhibited extreme pharmacological activities in treating a range of cancers. However, its …

Docetaxel (DTX), a semisynthetic analogue of paclitaxel, is often used to treat cancers.
Owing to its poor aqueous solubility, the current formulation of DTX for clinical applications …