Background Cell culture technology has spread prolifically within a century, a variety of
culture media has been designed. This review goes through the history, characteristics and …

Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

BACKGROUND The advances in the world of IVF during the last decades have been rapid
and impressive and culture media play a major role in this success. Until the 1980s fertility …

Lipids are a potential reservoir of energy for initial embryonic development before activation
of the embryonic genome and are involved in plasma membrane biosynthesis. Excessive …

A surprising set of recent observations suggests a link between assisted reproductive
technology (ART) and epigenetic errors—that is, errors involving information other than DNA …

The preimplantation mammalian embryo from different species appears sensitive to the
environment in which it develops, either in vitro or in vivo, for example, in response to culture …

Assisted reproductive technologies (ARTs) are becoming increasingly prevalent and are
generally considered to be safe medical procedures. However, evidence indicates that …

Mitochondria play a central and multifaceted role in the mammalian egg and early embryo,
contributing to many different aspects of early development. While the contribution of …

Contents Despite major efforts directed at improving the yield of blastocysts from immature
oocytes in vitro, the quality of such blastocysts continually lags behind that of blastocysts …

Energy homeostasis of the oocyte is a crucial determinant of fertility. Following ovulation, the
oocyte is exposed to the unique environment of the Fallopian tube, and this is reflected in a …