Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions

SK Sanganalmath, R Bolli - Circulation research, 2013 - Am Heart Assoc
Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …

[HTML][HTML] Advances in regenerative therapy: A review of the literature and future directions

EH Ntege, H Sunami, Y Shimizu - Regenerative therapy, 2020 - Elsevier
There is enormous global anticipation for stem cell-based therapies that are safe and
effective. Numerous pre-clinical studies present encouraging results on the therapeutic …

MSCs vs. iPSCs: Potential in therapeutic applications

K Thanaskody, AS Jusop, GJ Tye… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …

Stem cell therapy: a new therapeutic option for cardiovascular diseases

NH Goradel, FG Hour, B Negahdari… - Journal of cellular …, 2018 - Wiley Online Library
Cardiovascular diseases are known as one of major causes of morbidity and mortality
worldwide. Despite the many advancement in therapies are associated with cardiovascular …

Preclinical studies of stem cell therapy for heart disease

BA Tompkins, W Balkan, J Winkler… - Circulation …, 2018 - Am Heart Assoc
As part of the TACTICS (Transnational Alliance for Regenerative Therapies in
Cardiovascular Syndromes) series to enhance regenerative medicine, here, we discuss the …

[HTML][HTML] Stem cells as therapy for heart disease: iPSCs, ESCs, CSCs, and skeletal myoblasts

R Rikhtegar, M Pezeshkian, S Dolati, N Safaie… - Biomedicine & …, 2019 - Elsevier
Heart Diseases are serious and global public health concern. In spite of remarkable
therapeutic developments, the prediction of patients with Heart Failure (HF) is weak, and …

MUC1-C in chronic inflammation and carcinogenesis; emergence as a target for cancer treatment

DW Kufe - Carcinogenesis, 2020 - academic.oup.com
Chronic inflammation is a highly prevalent consequence of changes in environmental and
lifestyle factors that contribute to the development of cancer. The basis for this critical …

Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice

T Venit, O Sapkota, WS Abdrabou… - Nature …, 2023 - nature.com
Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that
nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. NM1 directly …

The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells

J MENENDEZ, J Joven, S Cufí, B Corominas-Faja… - Cell cycle, 2013 - Taylor & Francis
When fighting cancer, knowledge on metabolism has always been important. Today, it
matters more than ever. The restricted cataloging of cancer genomes is quite unlikely to …

Current tissue engineering strategies in anterior cruciate ligament reconstruction

NL Leong, FA Petrigliano… - Journal of biomedical …, 2014 - Wiley Online Library
Rupture of the anterior cruciate ligament (ACL) is one of the most common ligamentous
injuries of the knee. Limitations of allografts and autografts in ACL reconstruction as well as …