Emerging concepts in glaucoma and review of the literature
Glaucoma is the most commonly acquired optic neuropathy. It represents a public health
challenge because it causes an irreversible blindness. Emerging evidence indicates that the …
challenge because it causes an irreversible blindness. Emerging evidence indicates that the …
Recent developments in ocular drug delivery
H Chen - Journal of drug targeting, 2015 - Taylor & Francis
Ocular drug delivery has many challenges due to the inherent physiology and natural
barriers. Traditionally used eye drops are fairly inefficient with low ocular bioavailability, and …
barriers. Traditionally used eye drops are fairly inefficient with low ocular bioavailability, and …
Discovery of molecular therapeutics for glaucoma: challenges, successes, and promising directions: miniperspective
RK Donegan, RL Lieberman - Journal of medicinal chemistry, 2016 - ACS Publications
Glaucoma, a heterogeneous ocular disorder affecting∼ 60 million people worldwide, is
characterized by painless neurodegeneration of retinal ganglion cells (RGCs), resulting in …
characterized by painless neurodegeneration of retinal ganglion cells (RGCs), resulting in …
Recent developments in ophthalmic drug delivery systems for therapy of both anterior and posterior segment diseases
H Chen, Y Jin, L Sun, X Li, K Nan, H Liu… - Colloid and interface …, 2018 - Elsevier
Eye is a complex organ with unique anatomy and physiology. The structure of eye can be
divided into two main parts: anterior segment and posterior segment. Due to the special …
divided into two main parts: anterior segment and posterior segment. Due to the special …
Neuroprotection in the treatment of glaucoma–A focus on connexin43 gap junction channel blockers
YS Chen, CR Green, HV Danesh-Meyer… - European Journal of …, 2015 - Elsevier
Glaucoma is a form of optic neuropathy and a common cause of blindness, affecting over 60
million people worldwide with an expected rise to 80 million by 2020. Successful treatment …
million people worldwide with an expected rise to 80 million by 2020. Successful treatment …
Glaucoma: recent advances in the involvement of autoimmunity
Glaucomatous optic neuropathy is the most commonly acquired optic neuropathy
encountered in clinical practice. It is the second leading cause of blindness globally, after …
encountered in clinical practice. It is the second leading cause of blindness globally, after …
NAD+ and Niacin Supplementation as Possible Treatments for Glaucoma and Age-Related Macular Degeneration: A Narrative Review
Glaucoma and age-related macular degeneration (AMD) are progressive retinal diseases
characterized by increased oxidative stress, inflammation, and mitochondrial dysfunction …
characterized by increased oxidative stress, inflammation, and mitochondrial dysfunction …
Open-angle glaucoma: drug development pipeline during the last 20 years (1995-2015)
A Vicente, S Prud'homme, J Ferreira… - Ophthalmic …, 2017 - karger.com
Objectives: To analyse drug development for open-angle glaucoma during the last 20 years.
Methods: Research was performed by referring to clinical trials registered at the International …
Methods: Research was performed by referring to clinical trials registered at the International …
[HTML][HTML] Promise of latanoprost and timolol loaded combinatorial nanosheet for therapeutic applications in glaucoma
L Wang, YY Jiang, N Lin - Journal of King Saud University-Science, 2020 - Elsevier
To demonstrate a combinatorial drug loaded nanosheet made of alginate and chitosan
which reduces intraocular pressure in a slow and sustained manner depicted by in-vivo …
which reduces intraocular pressure in a slow and sustained manner depicted by in-vivo …
Translating the low translaminar cribrosa pressure gradient hypothesis into the clinical care of glaucoma
AH Guy, JL Wiggs, A Turalba… - Seminars in …, 2016 - Taylor & Francis
Glaucoma is an optic neuropathy with multiple known risk factors, including age, race, family
history, and intraocular pressure. Unfortunately, the only currently modifiable risk factor in …
history, and intraocular pressure. Unfortunately, the only currently modifiable risk factor in …