Side effects of methotrexate therapy for rheumatoid arthritis: A systematic review
W Wang, H Zhou, L Liu - European journal of medicinal chemistry, 2018 - Elsevier
Methotrexate (MTX) is used as an anchor disease-modifying anti-rheumatic drugs
(DMARDs) in treating rheumatoid arthritis (RA) because of its potent efficacy and tolerability …
(DMARDs) in treating rheumatoid arthritis (RA) because of its potent efficacy and tolerability …
Chinmedomics, a new strategy for evaluating the therapeutic efficacy of herbal medicines
Y Han, H Sun, A Zhang, G Yan, X Wang - Pharmacology & therapeutics, 2020 - Elsevier
Herbal medicines have accumulated valuable clinical experience in thousands of years of
applications in traditional Chinese medicine (TCM) or ethnomedicine. The unique multi …
applications in traditional Chinese medicine (TCM) or ethnomedicine. The unique multi …
[HTML][HTML] Chinmedomics: a powerful approach integrating metabolomics with serum pharmacochemistry to evaluate the efficacy of traditional Chinese medicine
AH Zhang, H Sun, GL Yan, Y Han, QQ Zhao, XJ Wang - Engineering, 2019 - Elsevier
Abstract Evaluation of the efficacy of traditional Chinese medicines (TCMs) is an important
prerequisite for discovering effective substances, lead compounds, and quality markers (Q …
prerequisite for discovering effective substances, lead compounds, and quality markers (Q …
Molecular toxicity of methotrexate in rheumatoid arthritis treatment: A novel perspective and therapeutic implications
Rheumatoid arthritis (RA) is an autoimmune inflammatory systematic complication which is a
chronic disorder that severely affects bones and joints and results in the quality of life …
chronic disorder that severely affects bones and joints and results in the quality of life …
[HTML][HTML] Gut microbiota as important modulator of metabolism in health and disease
X Wang, A Zhang, J Miao, H Sun, G Yan, F Wu… - RSC …, 2018 - pubs.rsc.org
The human gastrointestinal tract colonizes a large number of microbial microflora, forms a
host-microbiota co-metabolism structure with the host to participate in various metabolic …
host-microbiota co-metabolism structure with the host to participate in various metabolic …
[HTML][HTML] High-throughput metabolomics evaluate the efficacy of total lignans from acanthophanax senticosus stem against ovariectomized osteoporosis rat
A Zhang, Z Ma, H Sun, Y Zhang, J Liu, F Wu… - Frontiers in …, 2019 - frontiersin.org
Postmenopausal osteoporosis (PMOP) is a common clinical illness in postmenopausal
women, but there is no effective drug at present. Metabolomics approach was used to …
women, but there is no effective drug at present. Metabolomics approach was used to …
Discovery of quality-marker ingredients of Panax quinquefolius driven by high-throughput chinmedomics approach
H Xiong, A Zhang, Q Zhao, G Yan, H Sun, X Wang - Phytomedicine, 2020 - Elsevier
Background Quality control of traditional Chinese medicine (TCM) has always been a hot
issue to TCM. However, due to the complexity of TCM ingredients, the current quality …
issue to TCM. However, due to the complexity of TCM ingredients, the current quality …
[HTML][HTML] How do microorganisms influence the development of endometriosis? Participation of genital, intestinal and oral microbiota in metabolic regulation and …
A Sobstyl, A Chałupnik, P Mertowska… - International Journal of …, 2023 - mdpi.com
Microorganisms inhabiting the human body play an extremely key role in its proper
functioning, as well as in the development of the immune system, which, by maintaining the …
functioning, as well as in the development of the immune system, which, by maintaining the …
Guizhi Fuling Formulation: A review on chemical constituents, quality control, pharmacokinetic studies, pharmacological properties, adverse reactions and clinical …
X Liu, L Chen, P Sun, Z Zhan, J Wang - Journal of ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance Guizhi Fuling Formulation (GF), composed of
Cinnamomi Ramulus, Poria, Paeoniae Radix, Moutan Cortex, and Persicae Semen, was first …
Cinnamomi Ramulus, Poria, Paeoniae Radix, Moutan Cortex, and Persicae Semen, was first …
Structural characterization of a polysaccharide from Dioscorea opposita and assessment of its hepatoprotective activity
W Bu, W Dai, H Liu, H Bu, X Ju, R Li, B Yuan - Process Biochemistry, 2022 - Elsevier
A polysaccharide from Dioscorea opposita (DOP-2) was isolated, and structural analysis
revealed that DOP-2 was a heteropolysaccharide with an average molecular weight of 96.14 …
revealed that DOP-2 was a heteropolysaccharide with an average molecular weight of 96.14 …