[HTML][HTML] The role of the androgen receptor in prostate development and benign prostatic hyperplasia: A review
RE Vickman, OE Franco, DC Moline… - Asian journal of …, 2020 - Elsevier
Benign prostatic hyperplasia (BPH) is a benign enlargement of the prostate in which
incidence increases linearly with age, beginning at about 50 years old. BPH is a significant …
incidence increases linearly with age, beginning at about 50 years old. BPH is a significant …
[HTML][HTML] A cellular anatomy of the normal adult human prostate and prostatic urethra
A comprehensive cellular anatomy of normal human prostate is essential for solving the
cellular origins of benign prostatic hyperplasia and prostate cancer. The tools used to …
cellular origins of benign prostatic hyperplasia and prostate cancer. The tools used to …
Prostate luminal progenitor cells: from mouse to human, from health to disease
M Baures, C Dariane, E Tika, E Puig Lombardi… - Nature Reviews …, 2022 - nature.com
Stem and progenitor cells of the adult prostate epithelium have historically been believed to
reside mainly or exclusively within the basal cell compartment and to possess basal-like …
reside mainly or exclusively within the basal cell compartment and to possess basal-like …
[HTML][HTML] TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease
RE Vickman, LT Aaron-Brooks, R Zhang… - Nature …, 2022 - nature.com
Autoimmune (AI) diseases can affect many organs; however, the prostate has not been
considered to be a primary target of these systemic inflammatory processes. Here, we utilize …
considered to be a primary target of these systemic inflammatory processes. Here, we utilize …
5‐Alpha reductase inhibitors induce a prostate luminal to club cell transition in human benign prostatic hyperplasia
Benign prostatic hyperplasia (BPH) is a progressive expansion of peri‐urethral prostate
tissue common in aging men. Patients with enlarged prostates are treated with 5‐alpha …
tissue common in aging men. Patients with enlarged prostates are treated with 5‐alpha …
Urethral luminal epithelia are castration‐insensitive cells of the proximal prostate
Background Castration‐insensitive epithelial progenitors capable of regenerating the
prostate have been proposed to be concentrated in the proximal region based on facultative …
prostate have been proposed to be concentrated in the proximal region based on facultative …
[HTML][HTML] Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
D Liu, JE Shoag, D Poliak, RS Goueli… - Nature …, 2020 - nature.com
Benign prostatic hyperplasia (BPH), a nonmalignant enlargement of the prostate, is among
the most common diseases affecting aging men, but the underlying molecular features …
the most common diseases affecting aging men, but the underlying molecular features …
[HTML][HTML] Integrating spatial transcriptomics and single-cell RNA-sequencing reveals the alterations in epithelial cells during nodular formation in benign prostatic …
X Fei, J Liu, J Xu, H Jing, Z Cai, J Yan, Z Wu… - Journal of Translational …, 2024 - Springer
Objective Proliferative nodular formation represents a characteristic pathological feature of
benign prostatic hyperplasia (BPH) and serves as the primary cause for prostate volume …
benign prostatic hyperplasia (BPH) and serves as the primary cause for prostate volume …
[HTML][HTML] Functional heterogeneity of mouse prostate stromal cells revealed by single-cell RNA-seq
We perform a single-cell RNA sequencing analysis to investigate the phenotypic and
functional heterogeneity of the adult mouse prostate stromal cells. Our analysis identifies …
functional heterogeneity of the adult mouse prostate stromal cells. Our analysis identifies …
[HTML][HTML] Chronic inflammation promotes proliferation in the prostatic stroma in rats with experimental autoimmune prostatitis: study for a novel method of inducing …
M Zhang, C Luo, K Cui, T Xiong, Z Chen - World journal of urology, 2020 - Springer
Objective Inflammation plays an important role in the development of benign prostatic
hyperplasia (BPH). The aim of the present study was to reference the study of the …
hyperplasia (BPH). The aim of the present study was to reference the study of the …