Pharmacological activities of coumarin compounds in licorice: a review

Y Zang - Natural Product Communications, 2020 - journals.sagepub.com
Licorice is a traditional medicine commonly used in China and many other countries. Over
the last 50 years, the structure and pharmacological effects of coumarin compounds in …

VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents

EY Ahmed, NAA Latif, MF El-Mansy, WS Elserwy… - Bioorganic & Medicinal …, 2020 - Elsevier
Twenty five newly synthesized coumarin scaffold based derivatives were assayed for their in
vitro anticancer activity against MCF-7 breast and PC-3 prostate cancer cell lines and were …

1H-1, 2, 3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice …

A Rani, A Singh, J Kaur, G Singh, R Bhatti… - Bioorganic …, 2021 - Elsevier
The present paper explicates the synthesis of 1H-1, 2, 3-triazole tethered tacrine-chalcone
conjugates and evaluation of their AChE and BuChE inhibitory activity. In-vitro AChE …

Flavone Hybrids and Derivatives as Bioactive Agents

L Hazai, B Zsoldos, M Halmai, P Keglevich - Applied Sciences, 2024 - mdpi.com
Hybrid molecules can be defined as chemical entities with two or more structural domains,
namely pharmacophores, having a specific biological effect. In many cases, when at least …

Unmasking the efficacy of Skipjack Tuna (Katsuwonus Pelamis) dark muscle hydrolyzate in lipid regulation: a promising component for functional food

F Huang, Q Dai, K Zheng, Q Ma, Y Liu… - … Journal of Food …, 2023 - Taylor & Francis
To effectively utilize the by-products of skipjack tuna (Katsuwonus Pelamis) for the
preparation of peptides with lipid-lowering activity, alkaline proteinase was selected from six …

Kinetic and thermodynamic-based studies on the interaction mechanism of novel R. roxburghii seed peptides against pancreatic lipase and cholesterol esterase

H Yin, J Zhu, Y Zhong, D Wang, Y Deng - Food Chemistry, 2024 - Elsevier
Pancreatic lipase (PL) and cholesterol esterase (CE) are vital digestive enzymes that
regulate lipid digestion. Three bioactive peptides (LFCMH, RIPAGSPF, YFRPR), possessing …

New 1, 3, 4-Thiadiazole Derivatives and Investigation of their Biological Activity

AANF Al-Sharabi - 2022 - search.proquest.com
Alzheimer hastalığı (AH), yaşlılar arasında en sık görülen demans türü olan çok faktörlü bir
nörolojik bozukluktur. AH'nın patofizyolojisini açıklamak için çeşitli patojenik süreçler …