Although medical treatment of COPD has advanced, nonadherence to medication regimens
poses a significant barrier to optimal management. Underuse, overuse, and improper use …

Infections occur frequently in critically ill patients and their management can be challenging
for various reasons, including delayed diagnosis, difficulties identifying causative …

Gram-negative organisms comprise a large portion of the pathogens responsible for lower
respiratory tract infections, especially those that are nosocomially acquired, and the rate of …

Das Management von Asthma hat sich in den letzten Jahrzehnten fundamental gewandelt.
Die vorliegende Leitlinie zur Diagnostik und Therapie von Asthma wurde für pneumologisch …

Drug dosing in critically ill patients is challenging due to the altered drug pharmacokinetics–
pharmacodynamics associated with systemic therapies. For many drug therapies, there is …

Purpose To describe the practice, knowledge and beliefs about aerosol therapy during
mechanical ventilation in an international sample of physicians working in intensive care …

Inhaled antibiotics dramatically improve targeting of drug to the site of respiratory infections,
while simultaneously minimizing systemic exposure and associated toxicity. The high local …

Background Nebulization of antiinfective agents is a common but unstandardized practice in
critically ill patients. Methods A systematic review of 1,435 studies was performed in adults …

Background: High flow nasal cannula oxygen therapy (HFT) is increasingly used in intensive
and emergency care departments. Patients suffering from respiratory failure, who are likely …

Incremental gains in understanding the influence of various factors on aerosol delivery in
concert with technological advancements over the past 2 decades have fueled an ever …