Development of multiple intracranial aneurysms: beyond the common risk factors

TF Dinger, MD Oppong, C Park, M Said, M Chihi… - Journal of …, 2022 - thejns.org
OBJECTIVE The prevalence of multiple intracranial aneurysms (MIAs) has increased over
the last decades. Because MIAs have been identified as an independent risk factor for …

Aspirin treatment for unruptured intracranial aneurysms: Focusing on its anti-inflammatory role

Y Feng, H Zhang, S Dai, X Li - Heliyon, 2024 - cell.com
Intracranial aneurysms (IAs), as a common cerebrovascular disease, claims a worldwide
morbidity rate of 3.2%. Inflammation, pivotal in the pathogenesis of IAs, influences their …

The stability of the metabolic turnover of arachidonic acid in human unruptured intracranial aneurysmal walls is sustained

R Takeda, A Islam, T Sato, H Kurita, T Kahyo… - Clinical Neurology and …, 2021 - Elsevier
Objective Intracranial aneurysm (IA) is considered a chronic inflammatory condition that
affects intracranial arteries. Cyclooxygenase 2 (COX2) and prostaglandin E2 (PGE2) are …

Central intra-lesional iron deposits as a possible novel imaging marker at 7 Tesla MRI in Susac Syndrome-an exploratory study

D Strunk, T Sinnecker, I Kleffner, J Doerr… - BMC Medical …, 2024 - Springer
Abstract Background Susac syndrome (SuS) is a rare autoimmune disease that leads to
hearing impairment, visual field deficits, and encephalopathy due to an occlusion of …

Neutrophil-to-lymphocyte ratio associated with symptomatic saccular unruptured intracranial aneurysm

DX Zheng, YY Lv, XJ Zhang, JS Ye, JX Zhang… - European Journal of …, 2024 - Springer
Background and purpose Whether symptomatic unruptured intracranial aneurysms (UIAs)
lead to change in circulating inflammation remains unclear. This study aims to evaluate the …

[HTML][HTML] CD6 and CCR7 as Genetic Biomarkers in Evaluating Intracranial Aneurysm Rupture Risk

DD Xu, XQ Liu, ZS Wu - Journal of Integrative Neuroscience, 2024 - imrpress.com
Background: This study used bioinformatics combined with statistical methods to identify
plasma biomarkers that can predict intracranial aneurysm (IA) rupture and provide a strong …

Risk factor management matters more than pharmaceutical cyclooxygenase‐2 inhibition in the prevention of de novo intracranial aneurysms

S Räisänen, J Huttunen, TJ Huuskonen… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Pathophysiological studies of saccular intracranial aneurysm (sIA)
disease have shown that inflammation plays a crucial role in sIA development …

Intramural Hematoma in Vertebrobasilar Dolichoectasia–Related Stroke: A Retrospective Analysis of Six Consecutive Patients

M Itani, K Shimizu, H Imamura, S Tani, M Fujimoto… - World Neurosurgery, 2022 - Elsevier
Background The pathophysiology underlying vertebrobasilar dolichoectasia (VBD) is largely
unknown. However, a few reports have demonstrated that acute intramural hematoma (IMH) …

[HTML][HTML] Inflammation and Degeneration in the Saccular Intracranial Aneurysm Wall: The Role of Serum Amyloid A, Lymphatic Neovessels, and T-Lymphocytes

N Huuska - 2024 - helda.helsinki.fi
Materials and Methods A total of 36 sIA samples, comprising 16 unruptured and 20 ruptured
cases, were obtained during surgical clip ligation at Helsinki University Hospital …

Neurovascular disease

Z Zhang, AG van der Kolk, M Mossa-Basha… - Advances in Magnetic …, 2023 - Elsevier
Over the last decade, ultra-high field MRI at 7 Tesla (7T) has been used to study a variety of
brain disorders, including cerebrovascular diseases. The increased signal-to-noise and …