Synthetic glucocorticoids are widely used for their anti-inflammatory and
immunosuppressive actions. A possible unwanted effect of glucocorticoid treatment is …

Diabetes mellitus has emerged as a common comorbidity in cystic fibrosis and is considered
a clinical entity (cystic fibrosis-related diabetes, CFRD) distinct from that of type 1 diabetes …

The application of large-scale metabolomic profiling provides new opportunities for realizing
the potential of omics-based precision medicine for asthma. By leveraging data from over …

The pharmacokinetic and pharmacodynamic effects of inhaled corticosteroids (ICS) have
shaped the efficacy and safety of these agents in the treatment of asthma. Important …

Background: Until recently, only two cases of acute adrenal crisis associated with inhaled
corticosteroids (ICS) had been reported worldwide. We identified four additional cases and …

Background An adrenal crisis (AC) is a potential life‐threatening event in patients with
adrenal insufficiency (AI). This study aims to determine the incidence, causes, and risk …

Despite the availability of several formulations of inhaled corticosteroids (ICS) and delivery
devices for treatment of childhood asthma and despite the development of evidence-based …

Objective: To define the evidence for doses of inhaled corticosteroids in asthma and
describe this in clinically meaningful, evidence‐based terms. Data source: Cochrane …

Inhaled corticosteroids (ICSs) are the most effective anti-inflammatory agents available for
the treatment of asthma and represent the mainstay of therapy for most patients with the …

Objective. Our aim was to compare the 12-month safety and efficacy of fluticasone
propionate (FP) and sodium cromoglycate (SCG) in children aged 1 to 3 years with mild to …