Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …

Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …

Non-small cell lung cancer (NSCLC) is an obscure disease whose incidence is increasing
worldwide day by day, and PI3Kα is one of the major targets for cell proliferation due to the …

In the current study, series of 2-arylbenzimidazole-thiopyrimidine and-thioquinazolin-4 (3H)-
ones conjugates 12a-d, 13a, b and 14a-l have been synthesized. All the synthesized …

Epidermal growth factor receptor (EGFR) enhances lung cancer development, due to their
inability to permeate the cell membrane, secreted growth factors work through specialized …

Creating effective, ecologically friendly, and commercially viable synthetic routes is crucial in
the design and synthesis of organic substances. Quinazoline, a heterocyclic compound with …

Cancer cells have the ability of dysregulation and autonomous proliferation due to
unchecked production of definite molecules. These molecules are involved in the cell growth …

In this study, 16 new compounds were synthesized starting from methylparaben. These new
compounds consist of eight arylidenehydrazide derivatives and eight thiazolidin‐4‐on …

Histone deacetylases (HDACs), a class of enzymes responsible for the removal of acetyl
functional groups from the lysine residues in the amino-terminal tails of core histones, play a …

Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …