Bioinorganic Chemistry of Micronutrients Related to Alzheimer's and Parkinson's Diseases

A Kola, F Nencioni, D Valensin - Molecules, 2023 - mdpi.com
Metal ions are fundamental to guarantee the regular physiological activity of the human
organism. Similarly, vitamins play a key role in many biological functions of the metabolism …

Nanomedicine targets endogenous copper ions for disease diagnosis and therapy

X Li, Y Cui, T Zhou, J Li, P Lu, L Yuwen, L Wang… - Chemical Engineering …, 2023 - Elsevier
Copper ion is an essential microelement that plays vital roles in a wide range of
physiological processes, and aberrant copper levels in vivo usually cause various diseases …

Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials

D Huang, W Liao, J Li, T Chen, X Wang… - Advanced Functional …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that
constitutes the third most common cause of death among elderly individuals. AD patients …

Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies

V Das, JH Miller, CG Alladi, N Annadurai… - Medicinal Research …, 2024 - Wiley Online Library
As the world population ages, there will be an increasing need for effective therapies for
aging‐associated neurodegenerative disorders, which remain untreatable. Dementia due to …

A Combination of Heavy Metals and Intracellular Pathway Modulators Induces Alzheimer Disease-like Pathologies in Organotypic Brain Slices

DS Korde, C Humpel - Biomolecules, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
by amyloid-beta (Aβ) plaques and tau neurofibrillary tangles (NFT). Modelling aspects of AD …

Targeting Biometals in Alzheimer's Disease with Metal Chelating Agents Including Coumarin Derivatives

A Gucký, S Hamuľaková - CNS drugs, 2024 - Springer
Numerous physiological processes happening in the human body, including cerebral
development and function, require the participation of biometal ions such as iron, copper …

Zeolite and Neurodegenerative Diseases

S Panaiotov, L Tancheva, R Kalfin, P Petkova-Kirova - Molecules, 2024 - mdpi.com
Neurodegenerative diseases (NDs), characterized by progressive degeneration and death
of neurons, are strongly related to aging, and the number of people with NDs will continue to …

Subchronic Exposure to Mixture of Cadmium, Copper, and Nickel Induces Neurobehavioral Deficits and Hippocampal Oxidative Stress of Wistar Rats

M Lamtai, H Benmhammed, S Azirar… - … Trace Element Research, 2024 - Springer
The present study was aimed at evaluating the influence of the subchronic exposure of
cadmium (Cd), copper (Cu), and nickel (Ni) mixtures on affective behaviors, memory …

[HTML][HTML] Associations between plasma metal elements and risk of cognitive impairment among Chinese older adults

X Wang, B Wang, F Yang, K Shang, S Chen… - Frontiers in Aging …, 2024 - frontiersin.org
Background The relationship between plasma metal elements and cognitive function is
unclear, especially in extremely older individuals. This present study aimed to explore the …

Heavy metals toxicity on epigenetic modifications in the pathogenesis of Alzheimer's disease (AD)

D Venkatesan, S Muthukumar, M Iyer… - … of Biochemical and …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a progressive decline in cognitive ability and behavior which
eventually disrupts daily activities. AD has no cure and the progression rate varies unlikely …