Alkaloids from plants are characterised by structural diversity and bioactivity, and maintain a
privileged position in both modern and traditional medicines. In recent years, there have …

As sessile organisms, plants evolved elaborate metabolic systems that produce a plethora of
specialized metabolites as a means to survive challenging terrestrial environments …

Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary
metabolites with many medicinal properties, including the essential anti-cancer therapeutics …

Catharanthine can be coupled with vindoline to synthesize vinblastine and vincristine, which
have been used clinically as potent anticancer drugs. However, the structural complexity …

From the perspectives of pathway evolution, discovery and engineering of plant specialized
metabolism, the nature of the biosynthetic routes represents a critical aspect. Classical …

Covering: up to 2022 Plants produce a wide range of structurally and biosynthetically
diverse natural products to interact with their environment. These specialised metabolites …

The Lamiaceae family is renowned for its terpenoid-based medicinal components, but
Leonurus, which has traditional medicinal uses, stands out for its alkaloid-rich composition …

Psychoactive natural products play an integral role in the modern world. The tremendous
structural complexity displayed by such molecules confers diverse biological activities of …

Abstract The genus Salvia L.(Lamiaceae) comprises myriad distinct medicinal herbs, with
terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs) …

The spatial organization of genes within plant genomes can drive evolution of specialized
metabolic pathways. Terpenoids are important specialized metabolites in plants with diverse …