[HTML][HTML] Gap junctions and connexins in microglia-related oxidative stress and neuroinflammation: perspectives for drug discovery

G Caruso, L Di Pietro, F Caraci - Biomolecules, 2023 - mdpi.com
Microglia represent the immune system of the brain. Their role is central in two phenomena,
neuroinflammation and oxidative stress, which are at the roots of different pathologies …

[HTML][HTML] Research progress on the pharmacological activities of senkyunolides

Q Li, JB Wan, L Zhao - Acupuncture and Herbal Medicine, 2023 - journals.lww.com
Senkyunolides are a group of phthalide molecules that exist in Umbelliferae plants, with the
highest abundance in Ligusticum chuanxiong Hort, a medicinal herb with therapeutic …

A breakthrough in periodontitis treatment: Revealing the pharmacodynamic substances and mechanisms of Kouqiangjie formula

Y Wu, M Liu, X He, H Zhou, J Wei, H Li, Q Yuan… - Journal of …, 2024 - Elsevier
Ethnopharmacology relevance Periodontitis, a complex inflammatory disease, significantly
affects people's lives. Traditional Chinese multi-herbal formulas, composed of various herbs …

Icariin ameliorates the cuprizone-induced demyelination associated with antioxidation and anti-inflammation

LJ Song, QX Han, ZB Ding, K Liu, XX Zhang… - …, 2024 - Springer
The treatment of immunomodulation in multiple sclerosis (MS) can alleviate the severity and
relapses. However, it cannot improve the neurological disability of patients due to a lack of …

Integrated UPLC–Q‐TOF–MS and network pharmacology approach‐driven quality marker discovery of Danggui Shaoyao San for primary dysmenorrhea

Z Li, H Xiong, N Li, L Zhao, Z Liu, Y Yu… - Biomedical …, 2023 - Wiley Online Library
Abstract Danggui Shaoyao San (DSS), a famous prescription, has been clinically proved to
be effective in treating primary dysmenorrhea (PD). Currently there is no valid quality control …

[HTML][HTML] Jiawei Kongsheng Zhenzhong Pill: marker compounds, absorption into the serum (rat), and Q-markers identified by UPLC-Q-TOF-MS/MS

Q Wu, C Ou, J Wang, X Wu, Z Gao, Y Zhao… - Frontiers in …, 2024 - frontiersin.org
Background: The Jiawei Kongsheng Zhenzhong pill (JKZP), a Chinese herbal prescription
comprised of eight Chinese crude drugs, has been historically employed to treat …

[HTML][HTML] Effects of Mycobacterium vaccae NCTC 11659 and Lipopolysaccharide Challenge on Polarization of Murine BV-2 Microglial Cells

LW Desmond, EM Holbrook, CTO Wright… - International Journal of …, 2023 - mdpi.com
Previous studies have shown that the in vivo administration of soil-derived bacteria with anti-
inflammatory and immunoregulatory properties, such as Mycobacterium vaccae NCTC …

[HTML][HTML] Attenuated memory impairment and neuroinflammation in Alzheimer's disease by aucubin via the inhibition of ERK-FOS axis

C Wang, X Cui, Z Dong, Y Liu, P Xia, X Wang… - International …, 2024 - Elsevier
Alzheimer's disease (AD) is a degenerative illness accompanied by cognitive and memory
loss. In addition to the widely accepted, convincing amyloid cascade hypothesis, the …

[HTML][HTML] A comprehensive review of traditional Chinese medicine in treating neuropathic pain

H Naihua, L Jie, L Yong, L Yunxia - Heliyon, 2024 - cell.com
Neuropathic pain (NP) is a common, intractable chronic pain caused by nerve dysfunction
and primary lesion of the nervous system. The etiology and pathogenesis of NP have not yet …

KLF7 promotes LPS induced apoptosis, inflammation, and oxidative stress in H9c2 cells by activating NF-κB pathway.

G Hu, M Zhou, L Xu, D Wang - Science Asia, 2022 - search.ebscohost.com
This study aimed to investigate and explore the molecular mechanisms of Krüppel-like factor
7 (KLF7) on apoptosis, inflammation, and oxidative stress in H9c2 cells. In the study, the …