Non-adherence and deformability are the key intrinsic biomechanical features of the red
blood cell (RBC), which allow it to tightly squeeze and pass through even the narrowest of …

Iron deficiency (ID), the leading cause of anemia and the most common nutritional deficiency
globally, is not well reported among children in malaria-endemic settings, and little is known …

Sickle cell disease (SCD) is a lethal, life-long condition characterized by a mutation in the
gene that codes for hemoglobin. To alleviate the pain experienced by sickle cell (SC) …

Background. Sickle cell anaemia (SCA) is the most prevalent monogenic disease in Brazil.
In SCA, haemoglobin S (HbS) is formed, which modifies red blood cell morphology …

INTRODUCTION—The sickle point mutation in the beta globin gene results in the production
of sickle hemoglobin, which is less soluble than normal fetal or adult hemoglobin. Sickle cell …

Sickle cell disease is an inherited blood disorder indicative of red blood cells becoming
sickle-shaped. The study investigated the in vitro anti-sickling potentials of the seed oil of M …

Sickle cell anaemia (SCA) is an inherited, autosomal recessive condition that results from a
mutation in the β-globin gene. Vascular occlusion is the underlying mechanism behind a …

Introduction: nutritional status is an under-studied environmental factor that can impact the
phenotypic manifestations of patients with Sickle cell anaemia (SCA). This study aimed to …

ABSTRACT BMI percentile is a good index of nutritional status among pediatric patients. Yet
there is a dearth of information about the relationship between this important anthropometric …

Background: Majority of the literature regarding the pathophysiology of anaemia in sickle
cell disease (SCD) is focused on intravascular and extravascular red cell haemolysis with …