Idiopathic pulmonary fibrosis: Current and future treatment

DS Glass, D Grossfeld, HA Renna… - The clinical …, 2022 - Wiley Online Library
Objectives Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease characterized
by dry cough, fatigue, and progressive exertional dyspnea. Lung parenchyma and …

Survival in adult lung transplantation: where are we in 2020?

S Bos, R Vos, DE Van Raemdonck… - Current opinion in …, 2020 - journals.lww.com
Lung transplantation offers a survival benefit in well chosen patients with end-stage lung
diseases. However, CLAD, side effects of immunosuppressive therapy and solid organ …

[HTML][HTML] Consensus document for the selection of lung transplant candidates: an update from the International Society for Heart and Lung Transplantation

LE Leard, AM Holm, M Valapour, AR Glanville… - The Journal of Heart and …, 2021 - Elsevier
Tens of thousands of patients with advanced lung diseases may be eligible to be considered
as potential candidates for lung transplant around the world each year. The timing of referral …

Lung transplantation for idiopathic pulmonary fibrosis

PM George, CM Patterson, AK Reed… - The Lancet Respiratory …, 2019 - thelancet.com
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis.
Lung transplantation is the only intervention shown to increase life expectancy for patients …

Pulmonary hypertension associated with lung disease: new insights into pathomechanisms, diagnosis, and management

KM Olsson, TJ Corte, JC Kamp, D Montani… - The Lancet …, 2023 - thelancet.com
Patients with chronic lung diseases, particularly interstitial lung disease and chronic
obstructive pulmonary disease, frequently develop pulmonary hypertension, which results in …

Research progress in the molecular mechanisms, therapeutic targets, and drug development of idiopathic pulmonary fibrosis

H Ma, X Wu, Y Li, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Recent studies have
identified the key role of crosstalk between dysregulated epithelial cells, mesenchymal …

Lung transplantation for interstitial lung disease

SG Kapnadak, G Raghu - European Respiratory Review, 2021 - Eur Respiratory Soc
Lung transplantation (LTx) can be a life-extending treatment option for patients with
advanced and/or progressive fibrotic interstitial lung disease (ILD), especially idiopathic …

Regulatory immune cells in idiopathic pulmonary fibrosis: friends or foes?

C van Geffen, A Deißler, M Quante, H Renz… - Frontiers in …, 2021 - frontiersin.org
The immune system is receiving increasing attention for interstitial lung diseases, as
knowledge on its role in fibrosis development and response to therapies is expanding …

Targeting growth factor and cytokine pathways to treat idiopathic pulmonary fibrosis

H Ma, S Liu, S Li, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease of unknown origin
that usually results in death from secondary respiratory failure within 2–5 years of diagnosis …

Idiopathic pulmonary fibrosis (IPF): disease pathophysiology, targets, and potential therapeutic interventions

P Saha, P Talwar - Molecular and Cellular Biochemistry, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive, degenerative pulmonary condition.
Transforming growth factor (TGF)-β, platelet-derived growth factor (PDGF), and tumor …