Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …

The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Introduction of vaccines against COVID-19 has provided the most promising chance to
control the world-wide COVID-19 pandemic. However, the adenovirus-vector based …

White blood cells (WBCs) are immune cells that play essential roles in critical diseases
including cancers, infections, and inflammatory disorders. Their dynamic and diverse …

Skeletal muscle regeneration involves coordinated interactions between different cell types.
Injection of platelet-rich plasma is circumstantially considered an aid to muscle repair but …

Neutrophils are the most abundant circulating leukocytes in humans and the first immune
cells recruited at the site of inflammation. Classically perceived as short-lived effector cells …

CD8+ T cells are a major prognostic determinant in solid tumors, including colorectal cancer
(CRC). However, understanding how the interplay between different immune cells impacts …

In triple-negative breast cancer (TNBC), stromal restriction of CD8+ T cells associates with
poor clinical outcomes and lack of responsiveness to immune-checkpoint blockade (ICB). To …

In combination with immune checkpoint inhibitors, photodynamic therapy can induce robust
immune responses capable of preventing local tumor recurrence and delaying the growth of …