Solid dosage forms of biopharmaceuticals such as therapeutic proteins could provide
enhanced bioavailability, improved storage stability, as well as expanded alternatives to …

The poor solubility of significant number of Active Pharmaceutical Ingredients (APIs) has
become a major challenge in the drug development process. Drugs with poor solubility are …

In pharmaceutical research and development, various new chemical entities (NCE) are
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …

Pharmaceutical manufacturing is evolving from traditional batch processes to continuous
ones. The new global competition focused on throughput and quality of drug products is …

For inhalation drug delivery, amorphous powder formulations offer the benefits of increased
bioavailability for poorly soluble drugs, improved biochemical stability for biologics, and …

Dry powder inhalers have become increasingly attractive for pulmonary delivery of locally
and systemically effective medications. In comparison to the liquid counterparts, such as …

Highlights•The pulmonary route is an efficient route for respiratory diseases.•Technosphere
® and PulmoSphere™ are novel inhalable technologies for drug delivery.•Microparticles are …

Porous particles (PPs) are a novel kind of carrier with a large surface area, high porosity,
stable uniform porous structure, tunable pore sizes with narrow distribution, and well defined …

The particle formation process for microparticles of cellulose acetate butyrate dried from an
acetone solution was investigated experimentally and theoretically. A monodisperse droplet …

Localized pulmonary delivery of anticancer agents to lungs has proven to be pioneering
approach for lung cancer therapy. Hybrid lipid nanocore-protein shell nanoparticles …