Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty
C Badowski, B He, LX Garmire - NPJ precision oncology, 2022 - nature.com
Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
Nuclear long noncoding RNAs: key regulators of gene expression
A significant portion of the human genome encodes genes that transcribe long nonprotein-
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
Cancer stem cell functions in hepatocellular carcinoma and comprehensive therapeutic strategies
YC Liu, CT Yeh, KH Lin - Cells, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
Long non-coding RNAs and complex diseases: from experimental results to computational models
LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …
With the rapid advances in both experimental technology and computational prediction …
Long noncoding RNAs as biomarkers in cancer
L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches
AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …
support of clinical-pathological data such as the sum of the Gleason score and serum levels …
lncRNAs and microRNAs with a role in cancer development
J Liz, M Esteller - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2016 - Elsevier
Most diseases, including human cancer, are frequently associated with an altered
transcription pattern. The alteration of the transcriptome is not restricted to the production of …
transcription pattern. The alteration of the transcriptome is not restricted to the production of …
Pathogenic role of lncRNA-MALAT1 in endothelial cell dysfunction in diabetes mellitus
JY Liu, J Yao, XM Li, YC Song, XQ Wang, YJ Li… - Cell death & …, 2014 - nature.com
Long noncoding RNAs (lncRNAs) have important roles in diverse biological processes. Our
previous study has revealed that lncRNA-MALAT1 deregulation is implicated in the …
previous study has revealed that lncRNA-MALAT1 deregulation is implicated in the …
[HTML][HTML] HOTAIR: an oncogenic long non-coding RNA in different cancers
M Hajjari, A Salavaty - Cancer biology & medicine, 2015 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) refer to a group of RNAs that are usually more than 200
nucleotides and are not involved in protein generation. Instead, lncRNAs are involved in …
nucleotides and are not involved in protein generation. Instead, lncRNAs are involved in …
Long noncoding RNAs as novel biomarkers have a promising future in cancer diagnostics
T Shi, G Gao, Y Cao - Disease markers, 2016 - Wiley Online Library
Cancers have a high mortality rate due to lack of suitable specific early diagnosis tumor
biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are …
biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are …