Porcine epidemic diarrhea virus: Molecular mechanisms of attenuation and vaccines

Z Li, Z Ma, Y Li, S Gao, S Xiao - Microbial pathogenesis, 2020 - Elsevier
Porcine epidemic diarrhea virus (PEDV) causes an emerging and re-emerging coronavirus
disease characterized by vomiting, acute diarrhea, dehydration, and up to 100% mortality in …

Systematic review of animal-based indicators to measure thermal, social, and immune-related stress in pigs

RD Guevara, JJ Pastor, X Manteca, G Tedo, P Llonch - PloS one, 2022 - journals.plos.org
The intense nature of pig production has increased the animals' exposure to stressful
conditions, which may be detrimental to their welfare and productivity. Some of the most …

PEDV enters cells through clathrin-, caveolae-, and lipid raft-mediated endocytosis and traffics via the endo-/lysosome pathway

X Wei, G She, T Wu, C Xue, Y Cao - Veterinary Research, 2020 - Springer
With the emergence of highly pathogenic variant strains, porcine epidemic diarrhea virus
(PEDV) has led to significant economic loss in the global swine industry. Many studies have …

Aloe extract inhibits porcine epidemic diarrhea virus in vitro and in vivo

Z Xu, Y Liu, P Peng, Y Liu, M Huang, Y Ma, C Xue… - Veterinary …, 2020 - Elsevier
Porcine epidemic diarrhea virus (PEDV) causes severe diarrhoea and high mortality in
neonatal suckling piglets, leading to significant economic losses to the swine industry …

Insights and progress on epidemic characteristics, genotyping, and preventive measures of PEDV in China: A review

M Li, Y Pan, Y Xi, M Wang, Q Zeng - Microbial Pathogenesis, 2023 - Elsevier
Abstract Porcine Epidemic Diarrhoea (PED) is an acute, extremely infectious intestinal
disease of pigs caused by the Porcine Epidemic Diarrhoea Virus (PEDV). The virus can …

Pathogenicity of porcine deltacoronavirus (PDCoV) strain NH and immunization of pregnant sows with an inactivated PDCoV vaccine protects 5‐day‐old neonatal …

J Zhang, J Chen, Y Liu, S Da, H Shi… - Transboundary and …, 2020 - Wiley Online Library
In this study, the pathogenicity of porcine deltacoronavirus (PDCoV) strain NH (passage 10,
P10) was evaluated. We found that PDCoV strain NH is enteropathogenic in 5‐day‐old pigs …

Prevention and Control of Swine Enteric Coronaviruses in China: A Review of Vaccine Development and Application

F Kong, H Jia, Q Xiao, L Fang, Q Wang - Vaccines, 2023 - mdpi.com
Swine enteric coronaviruses (SECs) cause significant economic losses to the pig industry in
China. Although many commercialized vaccines against transmissible gastroenteritis virus …

Intranasally inoculated bacterium-like particles displaying porcine epidemic diarrhea virus S1 protein induced intestinal mucosal immune response in mice

K Su, Y Wang, C Yuan, Y Zhang, Y Li, T Li… - Frontiers in …, 2023 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) causes acute watery diarrhea and high mortality in
newborn piglets. Activation of intestinal mucosal immunity is crucial to anti-PEDV infection …

Hypericum japonicum extract inhibited porcine epidemic diarrhea virus in vitro and in vivo

H Rao, W Su, X Zhang, Y Wang, T Li, J Li… - Frontiers in …, 2023 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) infection causes lethal watery diarrhea and high
mortality in neonatal piglets, leading to huge economic losses in the global swine industry …

Efficacy of porcine epidemic diarrhea vaccines: A systematic review and meta-analysis

H Won, J Lim, YH Noh, I Yoon, HS Yoo - Vaccines, 2020 - mdpi.com
Porcine epidemic diarrhea (PED) is a devastating disease that causes considerable
economic damage to the global pig industry. Although the causative agent, the porcine …