Activity‐based smart AIEgens for detection, bioimaging, and therapeutics: Recent progress and outlook

H Li, H Kim, J Han, VN Nguyen, X Peng, J Yoon - Aggregate, 2021 - Wiley Online Library
Activity‐based approaches for designing AIEgens possess prominent advantages including
high selectivity, sensitivity, and signal‐to‐noise ratio, and they have received more attention …

AIEgen for cancer discrimination

R Zhang, X Huang, C Chen, RTK Kwok… - Materials Science and …, 2021 - Elsevier
Cancer is one of the most severe diseases and is challenging human health and longevity.
Cancer diagnosis is extremely important to improve the survival rate of patients. Cancer …

Clinical characteristics and outcomes of immune checkpoint inhibitor-induced pancreatic injury

H Abu-Sbeih, T Tang, Y Lu, S Thirumurthi… - … for immunotherapy of …, 2019 - Springer
Background Immune checkpoint inhibitor (ICI)-induced pancreatic injury (ICIPI) is not well
documented in the literature. We aimed to describe the clinical characteristics and outcomes …

Blockade of the protease ADAM17 ameliorates experimental pancreatitis

MI Saad, T Weng, J Lundy, LJ Gearing… - Proceedings of the …, 2022 - National Acad Sciences
Acute and chronic pancreatitis, the latter associated with fibrosis, are multifactorial
inflammatory disorders and leading causes of gastrointestinal disease-related …

The melatonin receptor agonist agomelatine protects against acute pancreatitis induced by cadmium by attenuating inflammation and oxidative stress and modulating …

RS Alruhaimi, EHM Hassanein, MK Abd El-Aziz… - International …, 2023 - Elsevier
Pancreatitis is a serious effect of the heavy metal cadmium (Cd) and inflammation and
oxidative stress (OS) are implicated in Cd-induced pancreatic injury. This study evaluated …

Safety of [177Lu]Lu-NeoB treatment: a preclinical study characterizing absorbed dose and acute, early, and late organ toxicity

EAM Ruigrok, M Verhoeven, MW Konijnenberg… - European Journal of …, 2022 - Springer
Purpose The radiolabeled gastrin-releasing peptide receptor (GRPR)-targeting antagonist
NeoB is a promising radioligand for imaging and therapy of GRPR-expressing …

Acute pancreatitis in pregnancy: a 10-year, multi-center, retrospective study in Beijing

T Zhang, G Wang, Z Cao, W Huang, H Xiao… - BMC pregnancy and …, 2022 - Springer
Objective Acute pancreatitis in pregnancy (APIP) is a rare and serious complication during
pregnancy. It has acute onset and is difficult to diagnose and treat. The aim of the present …

A combined “AIE+ ESIPT” fluorescent probe for detection of lipase activity

F Zhang, T Du, L Jiang, L Zhu, D Tian - Bioorganic Chemistry, 2022 - Elsevier
Lipases are acyl hydrolases that play a key role in fat digestion and monitoring of acute
pancreatitis by cleaving long-chain triglycerides into polar lipids. Due to an opposite polarity …

Serum D-dimer levels at admission for prediction of outcomes in acute pancreatitis

J Wan, X Yang, W He, Y Zhu, Y Zhu, H Zeng, P Liu… - BMC …, 2019 - Springer
Background Systemic alterations in coagulation are associated with complications of acute
pancreatitis (AP). D-dimer, a fibrin degradation product, was recently described as a marker …

The biological impacts of sitagliptin on the pancreas of a rat model of type 2 diabetes mellitus: Drug interactions with metformin

LM Shawky, AA Morsi, E El Bana, SM Hanafy - Biology, 2019 - mdpi.com
Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is a beneficial class of antidiabetic
drugs. However, a major debate about the risk of developing pancreatitis is still existing. The …