Nano-lantern on paper for smartphone-based ATP detection

MM Calabretta, R Álvarez-Diduk, E Michelini… - Biosensors and …, 2020 - Elsevier
ATP-driven bioluminescence relying on the D-luciferin-luciferase reaction is widely
employed for several biosensing applications where bacterial ATP detection allows to verify …

[HTML][HTML] Dysfunctional mitochondrial bioenergetics and synaptic degeneration in Alzheimer disease

J Tang, A Oliveros, MH Jang - International neurourology journal, 2019 - ncbi.nlm.nih.gov
Synapses are sites of high energy demand which are dependent on high levels of
mitochondrial derived adenosine triphosphate. Mitochondria within synaptic structures are …

Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway

B Yang, G Luo, C Zhang, L Feng, X Luo, L Gan - Scientific reports, 2020 - nature.com
Pseudorabies virus (PRV) infection can elicit nervous system disorders. Curcumin has been
reported to have neuroprotective effects. However, whether curcumin can protect neurons …

Photobiomodulation therapy attenuates hypoxic-ischemic injury in a neonatal rat model

LD Tucker, Y Lu, Y Dong, L Yang, Y Li, N Zhao… - Journal of Molecular …, 2018 - Springer
Photobiomodulation (PBM) has been demonstrated as a neuroprotective strategy, but its
effect on perinatal hypoxic-ischemic encephalopathy is still unknown. The current study was …

[HTML][HTML] Reactive oxygen species-independent apoptotic pathway by gold nanoparticles in Candida albicans

M Seong, DG Lee - Microbiological research, 2018 - Elsevier
Candida albicans is the most common pathogenic fungus in humans, causing cutaneous
and life-threatening systemic infections. In this study, we confirmed using propidium iodide …

Aging-dependent mitophagy dysfunction in Alzheimer's disease

M Song, X Zhao, F Song - Molecular Neurobiology, 2021 - Springer
Alzheimer's disease (AD) is the most common late-onset dementia characterized by the
deposition of extracellular amyloid plaques and formation of intracellular neurofibrillary …

Metformin protects PC12 cells and hippocampal neurons from H2O 2‐induced oxidative damage through activation of AMPK pathway

X Zhao, Z Zeng, U Gaur, J Fang, T Peng… - Journal of cellular …, 2019 - Wiley Online Library
Metformin, a first line anti type 2 diabetes drug, has recently been shown to extend lifespan
in various species, and therefore, became the first antiaging drug in clinical trial. Oxidative …

Activation of Nrf2 in astrocytes suppressed PD-like phenotypes via antioxidant and autophagy pathways in rat and Drosophila models

Q Guo, B Wang, X Wang, WW Smith, Y Zhu, Z Liu - Cells, 2021 - mdpi.com
The oxidative-stress-induced impairment of autophagy plays a critical role in the
pathogenesis of Parkinson's disease (PD). In this study, we investigated whether the …

Cellular stress and general pathological processes

EY Gusev, NV Zotova - Current Pharmaceutical Design, 2019 - ingentaconnect.com
From the viewpoint of the general pathology, most of the human diseases are associated
with a limited number of pathogenic processes such as inflammation, tumor growth …

Parkin, an E3 ubiquitin ligase, plays an essential role in mitochondrial quality control in Parkinson's disease

XL Wang, ST Feng, ZZ Wang, YH Yuan… - Cellular and Molecular …, 2021 - Springer
Abstract Parkinson's disease (PD), as one of the complex neurodegenerative disorders,
affects millions of aged people. Although the precise pathogenesis remains mostly …