[HTML][HTML] Piperidine based 1, 2, 3-triazolylacetamide derivatives induce cell cycle arrest and apoptotic cell death in Candida auris

V Srivastava, MY Wani, AS Al-Bogami… - Journal of advanced …, 2021 - Elsevier
Abstract Introduction: The fungal pathogen Candida auris, is a serious threat to public health
and is associated with bloodstream infections causing high mortality particularly in patients …

Phototherapy for age-related brain diseases: challenges, successes and future

L Ding, Z Gu, H Chen, P Wang, Y Song, X Zhang… - Ageing Research …, 2024 - Elsevier
Brain diseases present a significant obstacle to both global health and economic progress,
owing to their elusive pathogenesis and the limited effectiveness of pharmaceutical …

Meptyldinocap induces implantation failure by forcing cell cycle arrest, mitochondrial dysfunction, and endoplasmic reticulum stress in porcine trophectoderm and …

E Sung, W Park, J Park, FW Bazer, G Song… - Science of the Total …, 2024 - Elsevier
Meptyldinocap is a dinitrophenol fungicide used to control powdery mildew. Although other
dinitrophenol pesticides have been found to exhibit reproductive toxicity, studies of …

The puzzling role of neuron-specific PMCA isoforms in the aging process

T Boczek, T Radzik, B Ferenc, L Zylinska - International journal of …, 2019 - mdpi.com
The aging process is a physiological phenomenon associated with progressive changes in
metabolism, genes expression, and cellular resistance to stress. In neurons, one of the …

Carnosine ameliorates age-related dementia via improving mitochondrial dysfunction in SAMP8 mice

Z Dai, XY Lu, WL Zhu, XQ Liu, BY Li, L Song, HF Liu… - Food & function, 2020 - pubs.rsc.org
Dementia is a kind of age-related neurodegenerative disease. Carnosine, an endogenous
dipeptide consisting of β-alanine and L-histidine, has been shown to have neuroprotective …

Protein post-translational modifications–A challenge for bioelectrochemistry

EV Suprun - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Post-translational modifications (PTMs) occur during or after protein biosynthesis under the
action of various specific enzymes or reactive oxygen and nitrogen species. These …

PINK1 overexpression protects against cerebral ischemia through Parkin regulation

Y Wen, Y Gu, X Tang, Z Hu - Environmental toxicology, 2020 - Wiley Online Library
Mitochondrial dynamics and function are important for cell survival regulation under stress.
In this study, we report that cerebral ischemia/reperfusion (I/R) injury significantly reduced …

Aclonifen induces bovine mammary gland epithelial cell death by disrupting calcium homeostasis and inducing ROS production

J Park, G An, W Lim, G Song - Pesticide Biochemistry and Physiology, 2022 - Elsevier
Herbicides play key roles in agriculture. Aclonifen is a diphenyl ether herbicide that is widely
used for sunflower, potato, corn, and wheat crops. Since it has a long half-life, it is …

Opposite Roles of Co-enzyme Q10 and Formaldehyde in Neurodegenerative Diseases

J Xu, X Jin, Z Ye, D Wang, H Zhao… - American Journal of …, 2022 - journals.sagepub.com
Most of neurodegenerative diseases (NDD) have no cure. The common etiology of
neurodegenerations is unclear. Air pollutant-gaseous formaldehyde is notoriously known to …

Mechanistic understanding of dexamethasone-mediated protection against remdesivir-induced hepatotoxicity

K Liu, Z Li, L Li, S Heyward, SR Wang, L He… - Molecular …, 2024 - ASPET
Remdesivir (RDV), a broad-spectrum antiviral agent, is often used together with
dexamethasone (DEX) for hospitalized COVID-19 patients requiring respiratory support …