Despite the fact that MRI has evolved to become the standard method for diagnosis and
monitoring of patients with brain tumours, conventional MRI sequences have two key …

The most common type of primary brain tumor is malignant glioma. Despite intensive
therapeutic efforts, the majority of these neoplasms remain incurable. Imaging techniques …

Background Major depressive disorder is associated with raised peripheral inflammatory
markers. Mounting evidence also suggests that inflammation is involved in suicidal …

Translocator protein (TSPO) expression is increased in activated glia, and has been used as
a marker of neuroinflammation in PET imaging. However, the extent to which TSPO …

The inducible expression of the mitochondrial translocator protein 18 kDa (TSPO) by
activated microglia is a prominent, regular feature of acute and chronic-progressive brain …

Routine diagnostics and treatment monitoring of brain tumors is usually based on contrast-
enhanced MRI. However, the capacity of conventional MRI to differentiate tumor tissue from …

Background The ligands of mitochondrial translocator protein (TSPO) have been widely
used as diagnostic biomarkers for glioma. However, the true biological actions of TSPO in …

Simple Summary The translocator protein (TSPO) has been under extensive investigation as
a specific marker in positron emission tomography (PET) to visualize brain lesions following …

Objective The 18-kDa mitochondrial translocator protein (TSPO) was reported to be
upregulated in gliomas. 18 F-GE-180 is a novel 3rd generation TSPO receptor ligand with …

Background Inflammation is hypothesized to be a key event in the growth of sporadic
vestibular schwannoma (VS). In this study we sought to investigate the relationship between …